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Overview: Xdemvy eye drops are used to treat Demodex blepharitis, which is eyelid inflammation caused by tiny mites on your eyelashes. The medicine paralyzes the mites and eventually causes them to die. The most common side effects are temporary burning or stinging. Tell your healthcare provider right away if you have vision changes, an eye injury, eye surgery, or an eye infection while using Xdemvy.

Uses

What is Xdemvy used for?

Xdemvy is commonly used to treat eyelid swelling (inflammation) that is caused by tiny insects called Demodex mites, a condition known as Demodex blepharitis.

Learn more about treating demodex blepharitis with Xdemvy.

Xdemvy may also be used for other conditions as determined by your healthcare provider.

How does Xdemvy work (mechanism of action)?

Xdemvy is an eye drop that kills tiny mites (parasites) called Demodex. It works by blocking certain parts of the mites’ nerves, which paralyzes them and eventually causes them to die.

How is Xdemvy supplied (dosage forms)?

Brands and other names

  • Xdemvy

Dosage forms and strengths

  • 0.25% ophthalmic solution (eye drops)

How should I store Xdemvy?

Xdemvy should be stored at room temperature, between 59 F to 77 F (15 C to 25 C).

Side Effects

What are the most common side effects of Xdemvy?

The most common side effects of Xdemvy are burning and stinging after you put the drop in your eye. Tell your healthcare provider if you have any of these side effects that bother you.

There may be other side effects of Xdemvy that are not listed here. Contact your healthcare provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088. In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.

What are the serious side effects of Xdemvy?

While less common, the most serious side effects of Xdemvy are described below, along with what to do if they happen.

Severe Allergic Reactions. Xdemvy may cause allergic reactions, which can be serious. Stop using Xdemvy and get help right away if you have any of the following symptoms of a serious allergic reaction.

  • Breathing problems or wheezing
  • Racing heart
  • Fever or general ill feeling
  • Swollen lymph nodes
  • Swelling of the face, lips, mouth, tongue, or throat
  • Trouble swallowing or throat tightness
  • Itching, skin rash, or pale red bumps on the skin called hives
  • Nausea or vomiting
  • Dizziness, feeling lightheaded, or fainting
  • Stomach cramps
  • Joint pain

Warnings & Precautions

Who should not use Xdemvy?

Allergies to Ingredients. People who are allergic to any of the following should not use Xdemvy.

  • Xdemvy
  • Lotilaner
  • Any of the ingredients in the specific product dispensed

Your pharmacist can tell you all of the ingredients in Xdemvy.

What should I know about Xdemvy before using it?

Do not use Xdemvy unless it has been prescribed to you by a healthcare provider. Use it as prescribed. Several weeks of use may be needed for you to see improvement.

Do not share Xdemvy with other people, even if they have the same condition as you. It may harm them.

Keep Xdemvy out of the reach of children.

Xdemvy is an eye drop medicine. Make sure that you or a caregiver understands how to properly administer eye drops. It is important to complete your prescribed course of Xdemvy, even if your symptoms get better or go away. 

Eye infections may occur if your eye drop container gets contaminated with bacteria or other germs. In some cases, eye infections may become severe and lead to vision loss. To help prevent eye infections, be careful not to let the tip of the container touch your eye, face, fingers, or any other surfaces. Wash your hands before each use. 

Tell your healthcare provider right away if you have an eye injury, changes in vision, eye surgery, or an eye infection while using Xdemvy. Symptoms of an eye infection may include itchy or pink eyes, blurry vision or irritation, eye discharge, swollen eyelids, or fever.

Remove contact lenses before using Xdemvy. Then wait at least 15 minutes before you put your contacts back in. This medicine may discolor soft contact lenses.

If you use more than one eye medicine, separate them by at least five minutes. Ask your healthcare provider if you are unsure about when to use your eye medicines.

What should I tell my healthcare provider before using Xdemvy?

Tell your healthcare provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if Xdemvy is right for you.

In particular, make sure that you discuss any of the following.

Pregnancy. It is not known if or how Xdemvy could affect pregnancy or harm an unborn baby. Tell your healthcare provider if you are or plan to become pregnant. 

Breastfeeding. It is not known if Xdemvy passes into breast milk. Tell your healthcare provider if you are breastfeeding or plan to breastfeed. Your healthcare provider will advise you if you should use Xdemvy while breastfeeding.

How can I get more information about Xdemvy?

For more information about Xdemvy, you can visit the manufacturer’s website at www.xdemvy.com or call them at 888-421-4002.

Interactions

Does Xdemvy interact with foods or drinks?

There are no known interactions between Xdemvy and foods or drinks.

It is unknown if drinking alcohol will affect Xdemvy. 

Does Xdemvy interact with other medicines (drug interactions)?

There are no known interactions between Xdemvy and other medicines. Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.

Does interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose/Missed Dose

What should I do if I accidentally use too much Xdemvy?

If you or someone else has used too much Xdemvy, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.

What should I do if I miss a dose of Xdemvy?

If you miss a dose, skip the missed dose and use the next dose as scheduled. Do not use double or extra doses. 

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