Medically Reviewed by Jabeen Begum, MD on April 07, 2025
Psoriatic Arthritis Treatments
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Psoriatic Arthritis Treatments

When you have psoriatic arthritis, you may feel joint pain, swelling, and stiffness. To prevent damage to your joints and help you feel better, your treatment plan will focus on lowering inflammation. Many treatments can do this, but finding the right one for you will depend on your unique situation.

Over-the-Counter NSAIDs
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Over-the-Counter NSAIDs

If your symptoms aren't too severe, your doctor may recommend over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin, ibuprofen, and naproxen, to reduce pain and inflammation. These are often the first step in treating your psoriatic arthritis without a prescription.

Prescription NSAIDs
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Prescription NSAIDs

If your symptoms are more severe, you may be prescribed stronger NSAIDs. These include celecoxib, diclofenac, and indomethacin. These medications work well but can have side effects.

Steroids
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Steroids

Corticosteroids, such as prednisone and methylprednisolone, are powerful anti-inflammatory drugs. They can be used for short-term relief of severe symptoms but are not recommended for long-term use because of their side effects.

DMARDs
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DMARDs

Disease-modifying antirheumatic drugs (DMARDs) can slow down your disease progression. You may be given DMARDs such as leflunomide, methotrexate, or sulfasalazine. They can prevent joint damage over time and are used long-term.

Biologics
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Biologics

If your psoriatic arthritis symptoms are severe enough, your doctor may prescribe a biologic, such as TNF inhibitors or interleukin inhibitors. These block specific proteins that cause inflammation and joint damage. They can be very effective but may weaken your immune system, which leaves you at risk when you have the flu or another infection.

This content was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.