Preparation H Products for Hemorrhoids

Medically Reviewed by Beth Johnston, PharmD, BCPS on August 29, 2025
3 min read

Preparation H products are used to treat symptoms of hemorrhoids, which can include itching, burning, discomfort, irritation, swelling, and painful bowel movements.

The products come in different forms (wipes, creams, ointments, gels, sprays, and suppositories) and are safe for adults and children as young as 12 years old.

Preparation H products use different ingredients to target specific symptoms.

IngredientsPurpose
Protectants (like glycerin, petrolatum, or mineral oil)Create a barrier on your skin to lock in moisture and protect it from irritants and wetness
Anesthetics (like lidocaine or pramoxine)Numb the area by blocking nerve signals that cause pain or itching
Vasoconstrictors (like phenylephrine)Help with swelling and irritation by temporarily tightening the blood vessels
Astringents (like witch hazel)May also help with swelling and irritation by tightening blood vessels
Topical Corticosteroids (like hydrocortisone)Help with swelling, irritation, and itching

Most people don't have serious side effects. Stop using the medicine if you develop a rash or hives. Get medical help right away if you have signs of a serious allergic reaction, such as trouble breathing or swelling of the face, lips, or throat.

 

Stop using Preparation H products and call your health care provider if you have butt bleeding, your condition worsens or does not improve within seven days of using Preparation H, or if you have redness, irritation, swelling, pain, or other symptoms that are new or get worse. If you are using a Preparation H product that has an applicator and using the applicator causes more pain, stop using Preparation H and call your health care provider.

If you are using a Preparation H product that contains the ingredient phenylephrine, talk to your health care provider if you have any of the following before using the product. 

When using a Preparation H cream, ointment, gel, spray, or suppository, clean the affected area with a cleansing wipe before using the medicine, when practical.

There may be side effects, additional warnings, and interactions with other medicines that are not listed here. These may vary depending on the combination of ingredients in the specific Preparation H product you are using. Always check the label before taking any over-the-counter medicine. Do not use more than the recommended dose. Talk to your doctor or pharmacist about your health conditions and other medicines to help determine which products are safe for you.

Cleansing and Soothing Itch/Irritation

ProductKey Features
Medicated Hemorrhoidal WipesFlushable. Infused with aloe, chamomile, and cucumber.
Totables Medicated Hemorrhoidal WipesIndividually wrapped to easily take with you. Flushable and septic safe.
Medicated Hemorrhoidal Wipes for WomenInfused with cucumber, aloe, vitamin E, shea butter, and chamomile. Flushable and septic safe.

Swelling, Burning, and General Discomfort

These products use phenylephrine (a vasoconstrictor) to shrink swollen tissue, helping with pain and discomfort.

ProductKey Features
Hemorrhoidal SuppositoriesUsed for internal hemorrhoids.
Hemorrhoidal Cooling GelClear, nongreasy, and has no unpleasant smell. Also contains witch hazel.
Hemorrhoidal OintmentCan be used for internal and external relief. Also contains petrolatum & mineral oil.

Pain, Itching, and Multi-Symptom Relief

These products contain an anesthetic (lidocaine or pramoxine) to numb the area, giving strong relief from pain and itching, plus other ingredients for swelling and protection.

ProductKey Features
Multi-Symptom Relief Cream
  • Contains pramoxine (anesthetic), phenylephrine (vasoconstrictor), petrolatum, glycerin (protectants), and aloe
  • Offers comprehensive relief
Rapid Relief with Lidocaine Cream
  • Contains lidocaine (anesthetic), phenylephrine (vasoconstrictor), petrolatum, and glycerin (protectants)
  • Provides instant relief from pain
Rapid Relief with Lidocaine Spray
  • Contains lidocaine (anesthetic) and phenylephrine (vasoconstrictor)
  • Easy application without touching the area
Totables Rapid Relief with Lidocaine Wipes
  • Contains lidocaine (anesthetic), phenylephrine (vasoconstrictor), and glycerin (protectant)
  • Individually wrapped, flushable, and septic safe

Intense Itching

This product contains hydrocortisone (a topical corticosteroid) to treat severe itching and inflammation.

ProductKey Features
Soothing Relief Anti-Itch CreamFragrance-free