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Overview: Luliconazole is a cream used to treat athlete’s foot between the toes, jock itch, and ringworm. Skin irritation where the medicine is applied may happen. Luliconazole is for use on the skin only. Keep luliconazole away from areas such as your eyes, mouth, and vagina. Wash your hands after you use it.

Uses

What is luliconazole used for?

Luliconazole is commonly used to treat the following fungal skin infections.

Luliconazole may also be used for other conditions as determined by your health care provider.

How does luliconazole work (mechanism of action)?

Luliconazole is an antifungal medicine. It stops fungi from growing by preventing the formation of a needed part of their cell membranes. 

How is luliconazole supplied (dosage forms)?

Brands and other names

  • Luzu

Dosage forms and strengths

  • 1% topical cream

How should I store luliconazole?

Luliconazole should be stored at room temperature, between 68 F and 77 F (20 C and 25 C). It can be exposed to temperatures between 59 F and 86 F (15 C and 30 C) for shorter periods of time, such as when transporting it. Store in a cool, dry place. 

Side Effects

What are the most common side effects of luliconazole?

The most common side effect of luliconazole is mild skin irritation. Tell your health care provider if you have any side effects that bother you.

There may be other side effects of luliconazole that are not listed here. Contact your health care provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088 (800-332-1088). In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.

What are the serious side effects of luliconazole?

While less common, the most serious side effects of luliconazole are described below, along with what to do if they happen.

Severe Allergic Reactions. Luliconazole may cause allergic reactions, which can be serious. Stop using luliconazole and get help right away if you have any of the following symptoms of a serious allergic reaction.

  • Breathing problems or wheezing
  • Racing heart
  • Fever or general ill feeling
  • Swollen lymph nodes
  • Swelling of the face, lips, mouth, tongue, or throat
  • Trouble swallowing or throat tightness
  • Itching, skin rash, or pale red bumps on the skin called hives
  • Nausea or vomiting
  • Dizziness, feeling lightheaded, or fainting
  • Stomach cramps
  • Joint pain

Warnings & Precautions

Who should not use luliconazole?

Allergies to Ingredients. People who are allergic to any of the following should not use luliconazole.

  • Luliconazole
  • Luzu
  • Any of the ingredients in the specific product dispensed

Your pharmacist can tell you all of the ingredients in the specific luliconazole products they stock.

What should I know about luliconazole before using it?

Do not use luliconazole unless it has been prescribed to you by a health care provider. Use it as prescribed.

Do not share luliconazole with other people, even if they have the same condition as you. It may harm them.

Keep luliconazole out of the reach of children.

Luliconazole is for use on the skin only. Keep luliconazole away from areas such as your eyes, mouth, and vagina. 

Apply luliconazole to the infected skin area and to about 1 inch of the surrounding skin. Wash your hands after using it.

What should I tell my health care provider before using luliconazole?

Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them know if luliconazole is right for you.

In particular, make sure that you discuss any of the following.

Other Medicines and Supplements. Luliconazole may interact with other medicines and supplements. Before using luliconazole, tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details.

Pregnancy. It is not known if or how luliconazole could affect pregnancy or harm a fetus. Tell your health care provider if you are pregnant or plan to become pregnant.

Breastfeeding. It is not known if luliconazole passes into breast milk. Tell your health care provider if you are breastfeeding or plan to breastfeed. Your health care provider will let you know if you should use luliconazole while breastfeeding.

Interactions

Does luliconazole interact with foods or drinks?

There are no known interactions between luliconazole and foods or drinks.

It is unknown if drinking alcohol will affect luliconazole, but heavy drinking can slow your immune response and make it harder for your body to fight infections.

Does luliconazole interact with other medicines (drug interactions)?

Luliconazole may interact with certain medicines. Always tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.

Does interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose/Missed Dose

What should I do if I accidentally use too much luliconazole?

If you or someone else has used too much luliconazole, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.

What should I do if I miss a dose of luliconazole?

If you miss a dose, use it as soon as you remember. If it is almost time for your next dose, skip the missed dose and only use the next dose. Do not use double or extra doses. 

It is important to complete your prescribed course of luliconazole, even if your symptoms get better or go away. This will reduce the risk that future infections are resistant to luliconazole or other similar medicines.