Culturelle Probiotics

Medically Reviewed by Beth Johnston, PharmD, BCPS on September 11, 2025
3 min read

Culturelle probiotics can be used to support digestive and immune health. Probiotics are considered “good” bacteria. They are live microorganisms that can be found in fermented foods, such as yogurt. It is believed that the health of your gut can affect your immune system. Probiotics are believed to help support your digestive system by giving your gut “good” bacteria, which may also support your immune system. Antibiotics kill both “good” and “bad” bacteria in your body. Probiotics may also help your gut after taking antibiotics by replenishing the “good” bacteria. Probiotics may also be used to help support your vaginal health, urinary health, and mouth health. 

Some Culturelle products may also contain prebiotics. Prebiotics can be found in many types of food. They cannot be digested by your body and can also help “good” bacteria to grow in your gut. The probiotics found in Culturelle products include lactobacillus, bacillus, and bifidobacterium. The prebiotics found in some Culturelle products include inulin and 2-fucosyllactose. 

Some Culturelle products may also contain different vitamins, minerals, and other ingredients, which are listed below.

  • Vitamins: A, B5, B6, B7, B9, B12, C, D, E
  • Minerals: Zinc, iodine, magnesium, selenium, copper, manganese
  • Other ingredients: Lutein, elderberry, fish oil, DHA, ginger, lactase, alpha galactosidase, protease, cellulase, hemicellulase, phytase, invertase, myoviridae, siphoviridae

There are Culturelle probiotics for adults and children of all ages.

Stop using the product if you develop a rash or hives. Get medical help right away if you have signs of a serious allergic reaction, such as trouble breathing or swelling of the face, lips, or throat.

Some possible side effects include gas, bloating, or stomach gurgling when first starting the product. Talk to your health care provider before taking Culturelle, especially if you have a condition that weakens your immune system. Side effects may vary depending on the ingredients in the specific product you are using.

Talk to your health care provider if you have taken Culturelle probiotics for two weeks or more and are continuing to have gas, bloating, or stomach gurgling.

Always check the label before taking any over-the-counter product. Do not take more than the recommended dose.

If you are taking a probiotic to reduce the side effects of an antibiotic, take the probiotic dose at least 2 to 3 hours before or after your antibiotic dose to prevent the antibiotic from killing the good bacteria in the probiotic supplement.

There may be side effects, additional warnings, and interactions with medicines that are not listed here. These may vary depending on the combination of ingredients in the specific Culturelle product you are using. Always check the label before taking any over-the-counter product. Do not take more than the recommended dose. Talk to your doctor or pharmacist about your health conditions and medicines to help determine which products are safe for you.

To choose a Culturelle product, start by identifying your main health goal. The products are grouped by the specific problem they are formulated to address.

Primary Health Goal

Recommended Product Focus

Digestive upset - gas, bloating, diarrhea

Culturelle Digestive Daily Probiotic

  • Provides Lactobacillus rhamnosus GG (LGG), to support digestive health

Culturelle Bloating and Gas Defense

  • Provides LGG plus additional digestive enzymes and ginger root to support the body’s digestive process

Taking Antibiotics

Culturelle Ultimate Balance for Antibiotics 

  • Formulated to rebuild bacterial balance lost to antibiotic use

Women's Health (Vaginal, Urinary, Immune Support)

Culturelle Women’s 4in1 Protection

  • Provides LGG to support digestive health

Culturelle Women's Wellness

  • Provides LGG plus additional lactobacilli strains to balance bacteria and yeast in the vaginal microbiome

Immune Support 

Culturelle Health & Wellness

  • Provides LGG to support immune health

 Culturelle Immune Defense 

  • Provides LGG plus immune-supporting ingredients like vitamin C, vitamin D, or elderberry.)

Support for Children (Growth, development, tummy troubles)

Culturelle Kids Purely Probiotic

  • Provides LGG in easy to take gummies, chewables, and packets

Culturelle Kids Probiotic + Fiber

  • Provides LGG plus fiber for healthy digestion