5 mins read

Uses

What is Verquvo used for?

Verquvo (vericiguat) is commonly used to reduce your risk of going to the hospital or death from heart failure. Heart failure is a condition where the heart is not pumping as well as it should.

Verquvo may also be used for other conditions as determined by your healthcare provider.

How does Verquvo work (mechanism of action)?

Verquvo turns on a protein in your body called soluble guanylate cyclase (sGC), which relaxes blood vessels, including those in your heart. Relaxing these blood vessels provides more blood and oxygen to your heart muscle, allowing it to work better.

How is Verquvo supplied (dosage forms)?

Verquvo is available in the following dosage forms that are taken by mouth.

  • 2.5 mg oral tablets
  • 5 mg oral tablets
  • 10 mg oral tablets

How should I store Verquvo?

Verquvo should be stored at room temperature, between 68 F to 77 F (20 C to 25 C). It can be exposed to temperatures between 59 F to 86 F (15 C to 30 C), for shorter periods of time, such as when transporting it. Store in a cool, dry place.

Side Effects

What are the most common side effects of Verquvo?

The most common side effects of Verquvo are listed below. Tell your healthcare provider if you have any of these side effects that bother you.

There may be other side effects of Verquvo that are not listed here. Contact your healthcare provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088. In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.

What are the serious side effects of Verquvo?

While less common, the most serious side effects of Verquvo are described below, along with what to do if they happen.

Severe Allergic Reactions. Verquvo may cause allergic reactions, which can be serious. Stop taking Verquvo and get help right away if you have any of the following symptoms of a serious allergic reaction.

  • Breathing problems or wheezing
  • Racing heart
  • Fever or general ill feeling
  • Swollen lymph nodes
  • Swelling of the face, lips, mouth, tongue, or throat
  • Trouble swallowing or throat tightness
  • Itching, skin rash, or pale red bumps on the skin called hives
  • Nausea or vomiting
  • Dizziness, feeling lightheaded, or fainting
  • Stomach cramps
  • Joint pain

Warnings & Precautions

Who should not use Verquvo?

Pregnancy. Do not take Verquvo if you are pregnant. If you become pregnant, contact your healthcare provider right away. See the Pregnancy section for more details.

Drug Interactions. Verquvo should not be taken while you are using certain other medicines. Before taking Verquvo, tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details.

Allergies to Ingredients. People who are allergic to any of the following should not take Verquvo.

  • Verquvo
  • Vericiguat
  • Any of the ingredients in the specific product dispensed

Your pharmacist can tell you all of the ingredients in Verquvo.

What should I know about Verquvo before using it?

Do not take Verquvo unless it has been prescribed to you by a healthcare provider. Take it as prescribed.

Do not share Verquvo with other people, even if they have the same condition as you. It may harm them.

Keep Verquvo out of the reach of children.

Take Verquvo with food.

Swallow Verquvo tablets whole.  If you have trouble swallowing Verquvo whole, you may crush the tablets and mix with water right before taking.

What should I tell my healthcare provider before using Verquvo?

Tell your healthcare provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if Verquvo is right for you.

In particular, make sure that you discuss any of the following.

Pregnancy. Verquvo may cause harm to an unborn baby. Tell your healthcare provider if you are or plan to become pregnant. If you become pregnant, stop taking Verquvo right away and contact your healthcare provider. You must have a negative pregnancy test before starting Verquvo. If you can become pregnant, use effective forms of birth control while taking Verquvo and for 1 month after your last dose.

If you become pregnant while taking Verquvo, you can report this by calling 877-888-4231 or visiting pregnancyreporting.verquvo-us.com. This will take you to the United States (U.S.) Pregnancy Surveillance Program page for Verquvo, where you can share your experiences and be monitored for any safety issues. 

Breastfeeding. It is not known if Verquvo passes into breast milk. Tell your healthcare provider if you are breastfeeding or plan to breastfeed. Your healthcare provider will advise you if you should stop breastfeeding or stop Verquvo. If you take Verquvo, you should not breastfeed.

How can I get more information about Verquvo?

For more information about Verquvo, you can visit the manufacturer’s website at www.verquvo-us.com or call them at 855-272-5121.

Interactions

Does Verquvo interact with foods or drinks?

There are no known interactions between Verquvo and foods or drinks.

It is unknown if drinking alcohol will affect Verquvo. However, alcohol may increase your risk for low blood pressure while taking Verquvo, which can cause dizziness or make you feel lightheaded.

Does Verquvo interact with other medicines (drug interactions)?

Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.

In particular, make sure that you discuss if you are using any of the following before using Verquvo.

  • Any other type of medicine called a soluble guanylate cyclase (sGC) stimulator, such as riociguat (Adempas)
  • A type of medicine called a phosphodiesterase-5 (PDE-5) inhibitor, such as avanafil (Stendra), sildenafil (Viagra, Revatio, and others), tadalafil (Cialis and others), or vardenafil (Levitra, Staxyn), which are used for erectile dysfunction and pulmonary arterial hypertension (PAH)

This may not be a complete list of medicines that can interact with Verquvo. Always check with your healthcare provider.

Does interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose/Missed Dose

What should I do if I accidentally use too much Verquvo?

If you or someone else has used too much Verquvo, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.

What should I do if I miss a dose of Verquvo?

If you miss a dose, take the missed dose as soon as you remember on the same day of the missed dose. Do not take 2 doses on the same day to make up for a missed dose.