Goody’s Products for Pain, Headache, and Hangover Relief

Medically Reviewed by Beth Johnston, PharmD, BCPS on September 09, 2025
4 min read

Goody’s products are used to treat common aches and pains, including headaches, backaches, muscle aches, and hangover symptoms. They come in a powder form that you can take quickly for relief.

Goody’s products mix multiple pain-relieving ingredients in one dose.

  • Acetaminophen helps relieve pain by blocking pain signals in your body.
  • Aspirin helps relieve pain and is a type of medicine called an NSAID (nonsteroidal anti-inflammatory). NSAIDs work by blocking specific proteins in your body that cause swelling and pain.
  • Caffeine helps relieve pain and can make you feel more awake by speeding up your nervous system.

One Goody’s product (Goody’s PM Nighttime Powder) also contains an active ingredient known as diphenhydramine. Diphenhydramine is an antihistamine that works to block a chemical in your body called histamine, which can work to help you fall asleep.

Goody’s products are generally safe for adults and children as young as 12 years old.

Stop using the medicine if you develop a rash or hives. Get medical help right away if you have signs of a serious allergic reaction, such as trouble breathing or swelling of the face, lips, or throat.

Common Side Effects 

Since these products contain many ingredients, side effects can vary. Some common ones include the following.

  • Stomach problems
  • Trouble sleeping or feeling restless (from caffeine)
  • Drowsiness or dizziness (from diphenhydramine)
  • Nervousness or a rash

Goody’s products come as a powder. You can take the medicine one of two ways. The first way is to place it on your tongue and take it with a full glass of water. The second way is to mix the powder with water or another liquid in a glass. If you are taking a Goody’s product that has aspirin, you may be at higher risk of developing Reye’s syndrome (in children and teenagers) and stomach bleeding. If you are taking a Goody’s product for hangover relief, do not use the medicine for more than two days unless you are told so by your health care provider. Some Goody’s products that contain caffeine may have as much caffeine as a cup of coffee. Taking other medicines with caffeine or drinking coffee while taking some Goody’s products with caffeine may cause irritability, fast heartbeat, and nervousness.

Check with a health care provider if you have any of the following before taking a Goody’s product with aspirin.

Stop taking Goody’s and call your health care provider if you have any of the following symptoms.

  • Bloody or black stool
  • Feeling faint
  • Vomit blood or have new stomach pain
  • Ringing in your ears or hearing loss
  • Develop any new symptoms
  • Pain that gets worse or lasts for 10 days or more
  • Fever that gets worse or lasts for three days or more
  • Redness or swelling

If you are taking Goody’s PM Nighttime powder (which contains diphenhydramine), the medicine can make you drowsy. If you feel drowsy after taking this product, do not drive or do other activities that require alertness or coordination until you know how the product affects you. Drinking alcohol can increase your risk for drowsiness. Avoid drinking alcohol while taking Goody’s PM Nighttime powder. Before taking a Goody’s product with diphenhydramine, check with your health care provider if you have any of the following.

There may be side effects, additional warnings, and interactions with other medicines that are not listed here. These may vary depending on the combination of ingredients in the specific Goody’s product you are using. Always check the label before taking any over-the-counter medicine. Do not take more than the recommended dose. Talk to your doctor or pharmacist about your health conditions and other medicines to help determine which products are safe for you.

Primary symptomsRecommended Products (Ingredients)
Quick Relief for Headaches, Aches, and PainGoody’s Extra Strength Headache Powder (aspirin 520 mg, acetaminophen 260 mg, caffeine 32.5 mg)
Hangover or Need Mental Alertness

Goody’s Hangover Powder or Goody’s Plus Headache Pain + Mental Alertness Powder (aspirin 1000 mg, caffeine 150 mg)

*Do not use for more than two days unless a doctor tells you to

Need Pain Relief While SleepingGoody’s PM Nighttime Powder (acetaminophen 500 mg, diphenhydramine 38 mg)
General Pain (headache, muscle, arthritis, cold, fever)Goody’s Cool Orange Powder or Goody’s Mixed Fruit Blast Headache Powder (aspirin 500 mg, acetaminophen 325 mg, caffeine 65 mg)
Headache, Backache, Muscle Ache, Minor Arthritis Pain, Toothache, Menstrual Cramps, Common ColdGoody’s Cool Orange Powder or Goody’s Mixed Fruit Blast Headache Powder (aspirin 500 mg, acetaminophen 325 mg, caffeine 65 mg)