Uses
Side Effects
Warnings & Precautions
Interactions
Overdose/Missed Dose
Reviews Elahere is commonly used to treat several cancers. Common side effects include changes in liver function tests, blurred vision, and nausea. Call your healthcare provider right away if you have a cough, shortness of breath, or trouble breathing. Elahere is an infusion into your vein (IV) given by your healthcare provider.
Uses
What is Elahere used for?
Elahere (mirvetuximab soravtansine-gynx) is commonly used to treat certain ovarian, fallopian tube, and peritoneal cancers.
Your Guide to Elahere for Ovarian, Fallopian Tube, or Peritoneal Cancer
Elahere may also be used for other conditions as determined by your healthcare provider.
How does Elahere work (mechanism of action)?
Elahere is an antibody drug conjugate that works by targeting a specific protein that is on the surface of some cancer cells. It then attaches itself to this protein and delivers a chemotherapy medicine to the cell that kills the cancer cell. This prevents cancer tumors from growing and makes the cancer shrink in size.
How is Elahere supplied (dosage forms)?
Brands and other names
- Elahere
Dosage forms and strengths
Elahere is available in an injectable form that is given by a healthcare provider.
How should I store Elahere?
Elahere is usually given by a healthcare provider in a hospital or clinic. You will not store it at home.
Side Effects
What are the most common side effects of Elahere?
The most common side effects of Elahere are listed below. Tell your healthcare provider if you have any of these side effects that bother you.
- Changes in liver function tests
- Tiredness
- Eye problems (see below)
- Nausea and vomiting
- Diarrhea or constipation
- Stomach pain
- Nerve problems (see below)
- Muscle and bone pain
- Low levels of blood cell counts
- Decreased magnesium level in your blood
- Loss of appetite
There may be other side effects of Elahere that are not listed here. Contact your healthcare provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088. In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.
What are the serious side effects of Elahere?
While less common, the most serious side effects of Elahere are described below, along with what to do if they happen.
Severe Allergic Reactions. Elahere may cause allergic reactions, which can be serious. Get help right away if you have any of the following symptoms of a serious allergic reaction.
- Breathing problems or wheezing
- Racing heart
- Fever or general ill feeling
- Swollen lymph nodes
- Swelling of the face, lips, mouth, tongue, or throat
- Trouble swallowing or throat tightness
- Itching, skin rash, or pale red bumps on the skin called hives
- Nausea or vomiting
- Dizziness, feeling lightheaded, or fainting
- Stomach cramps
- Joint pain
Eye Problems. Elahere may cause eye problems, including severe problems such as swelling (uveitis) or inflammation of the cornea (keratitis). Keep all appointments to have your eyes checked. Do not wear contact lenses unless your healthcare provider tells you otherwise. Your healthcare provider will give you certain eye drops to use while you are receiving Elahere. Use the eye drops exactly as instructed and contact your healthcare provider right away if you have any of the following symptoms.
- Eye redness, itchiness, or pain
- Swollen or itchy eyelids
- Feeling like you have something in your eye
- Eye dryness, watering, or discharge
- Vision changes, such as blurry vision or sensitivity to light
Lung Inflammation. Elahere can cause inflammation in your lungs, also called interstitial lung disease or pneumonitis. This can be serious or even life-threatening. Get emergency help if you have trouble breathing. You may also have a cough, fever, or chest pain.
Nerve Problems. Nerves are the fibers that carry sensations from your body to the brain. Damage to these nerves, called peripheral neuropathy, can happen in people who are using Elahere. Call your healthcare provider if you develop pain, burning, tingling, numbness, or weakness in your arms, hands, legs, or feet.
Warnings & Precautions
Who should not use Elahere?
Allergies to Ingredients. People who are allergic to any of the following should not use Elahere.
- Mirvetuximab soravtansine
- Elahere
- Any of the ingredients in the specific product dispensed
Your pharmacist can tell you all of the ingredients in Elahere.
What should I know about Elahere before using it?
Do not use Elahere unless it has been prescribed to you by a healthcare provider. Elahere is usually given by a healthcare provider in a hospital or clinic.
Your healthcare provider will give you medicines to take before each dose to prevent nausea, vomiting, and certain reactions that may happen during the infusion. Take these medicines exactly as they tell you to.
What should I tell my healthcare provider before using Elahere?
Tell your healthcare provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if Elahere is right for you.
In particular, make sure that you discuss any of the following.
Current and Past Health Conditions. Tell your healthcare provider if you have any of the following.
- Eye problems
- Liver problems
- Nerve problems including numbness or tingling in your hands or feet
- Lung or breathing problems
Other Medicines and Supplements. Elahere may interact with other medicines and supplements. Before using Elahere, tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details.
Pregnancy. Elahere can harm an unborn baby. If you are able to get pregnant, your healthcare provider will make sure you are not pregnant before you start using the medicine. If you are able to get pregnant, you will need to use effective birth control while receiving Elahere and for seven months after your last dose. Tell your healthcare provider if you are or plan to become pregnant.
Breastfeeding. Do not breastfeed while receiving Elahere and for one month after your last dose. It is not known if Elahere passes into breast milk. Tell your healthcare provider if you are breastfeeding or plan to breastfeed.
How can I get more information about Elahere?
For more information about Elahere, you can visit the manufacturer’s website at www.elahere.com or call them at 833-353-4373.
Interactions
Does Elahere interact with foods or drinks?
There are no known interactions between Elahere and foods or drinks.
It is unknown if drinking alcohol will affect Elahere, but heavy drinking can slow your immune response and make it harder for your body to fight cancer.
Does Elahere interact with other medicines (drug interactions)?
Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.
In particular, make sure that you discuss if you are using any of the following before using Elahere.
- Ketoconazole, itraconazole (Sporanox, Tolsura), posaconazole (Noxafil), or voriconazole (Vfend), which is a medicine used for fungal infections
- Nefazodone, which is a medicine used to treat depression
- Clarithromycin, which is a medicine used for bacterial infections
Some other medicines may alter the blood levels of Elahere. Tell your healthcare provider about all medicines that you take or have recently taken.
This may not be a complete list of medicines that can interact with Elahere. Always check with your healthcare provider.
Overdose/Missed Dose
What should I do if I accidentally use too much Elahere?
If you or someone else has used too much Elahere, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.
What should I do if I miss a dose of Elahere?
Elahere is usually given by a healthcare provider in a hospital. Your healthcare provider will make sure you are receiving Elahere as scheduled.
If you miss an appointment to get your Elahere dose, call to make another appointment as soon as possible.