Tryptyr (acoltremon): Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

5 mins read

Overview: Tryptyr is an eye drop used for dry eye disease. It works by helping your eyes make more tears. The most common side effects are pain or burning when you put the drop in your eye. If you use another eye medicine, wait at least five minutes between Tryptyr and the other eye medicine. If you wear contact lenses, take them out before using Tryptyr, and wait 15 minutes to put your contact lenses back in your eyes. Call your health care provider right away if you get an eye infection or injury.

Uses

What is Tryptyr used for?

Tryptyr (acoltremon) is commonly used to treat symptoms of dry eye disease.

Learn more about Tryptyr for dry eye disease.

Tryptyr may also be used for other conditions as determined by your health care provider.

How does Tryptyr work (mechanism of action)?

Tryptyr is thought to work by stimulating certain nerves in your cornea, which increases the amount of tears you make. Tears can reduce the symptoms of dry eye disease, such as eye itching, a sandy or gritty feeling in your eyes, eye redness, and blurry vision.

How is Tryptyr supplied (dosage forms)?

Brands and other names

Tryptyr

Dosage forms and strengths

0.003% ophthalmic solution (eye drops) in single-dose vials

How should I store Tryptyr?

Tryptyr comes in single-dose containers in foil pouches and packed in cartons. Store unopened cartons of Tryptyr in the refrigerator, between 36 F and 46 F (2 C and 8 C). After opening the carton, you can keep Tryptyr at room temperature up to 77 F (25 C) for up to 30 days or in the refrigerator. Keep the single-dose containers in the foil pouches to protect them from light until you are ready to use them. After you open a foil pouch, throw away any unused single-dose containers after 7 days.

Side Effects

What are the most common side effects of Tryptyr?

The most common side effects of Tryptyr are listed below. Tell your health care provider if you have any of these side effects that bother you.

Eye pain when you put the drop in your eye
Stinging or burning feeling

There may be other side effects of Tryptyr that are not listed here. Contact your health care provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088 (800-332-1088). In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.

What are the serious side effects of Tryptyr?

While less common, the most serious side effects of Tryptyr are described below, along with what to do if they happen.

Severe Allergic Reactions. Tryptyr may cause allergic reactions, which can be serious. Stop using Tryptyr and get help right away if you have any of the following symptoms of a serious allergic reaction.

Breathing problems or wheezing
Racing heart
Fever or general ill feeling
Swollen lymph nodes
Swelling of the face, lips, mouth, tongue, or throat
Trouble swallowing or throat tightness
Itching or skin rash
Bumps on the skin called hives that can be red, pink, white, or brown depending on your skin tone
Nausea or vomiting
Dizziness, feeling lightheaded, or fainting
Stomach cramps

Warnings & Precautions

Who should not use Tryptyr?

Allergies to Ingredients. People who are allergic to any of the following should not use Tryptyr.

Acoltremon
Tryptyr
Any of the ingredients in the specific product dispensed

Your pharmacist can tell you all of the ingredients in Tryptyr.

What should I know about Tryptyr before using it?

Do not use Tryptyr unless it has been prescribed to you by a health care provider. Use it as prescribed.

Do not share Tryptyr with other people, even if they have the same condition as you. It may harm them.

Keep Tryptyr out of the reach of children. When Tryptyr is kept in the refrigerator, take special precautions to keep it away from children who also use the refrigerator.

Tryptyr is an eye drop medicine. Make sure that you or a caregiver understands how to properly administer eye drops. Read and follow the instructions that come with Tryptyr. If you have any questions, talk to your health care provider.

Eye infections may occur if Tryptyr gets contaminated with bacteria or other germs. To help prevent eye injury or infections, be careful not to let the tip of the container touch your eye, fingers, or any other surfaces. Wash your hands before each use. If you get an eye injury or infection, call your health care provider right away.

Tryptyr eye drops come in single-use containers that have enough medicine to treat one or both of your eyes, as prescribed. There is a little extra medicine in each container in case you miss getting the drop into your eye on the first try. After you use Tryptyr, throw away the container. Do not save any leftover medicine.

If you use more than one eye medicine, use them at least five minutes apart. Ask your healthcare provider if you are unsure when to use your eye medicines.

Remove contact lenses before using Tryptyr. Then wait at least 15 minutes after using Tryptyr before putting your contact lenses back in.

What should I tell my health care provider before using Tryptyr?

Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them know if Tryptyr is right for you.

In particular, make sure that you discuss any of the following.

Pregnancy. It is not known if or how Tryptyr could affect pregnancy or harm an unborn baby. Tell your healthcare provider if you are pregnant or plan to become pregnant.

Breastfeeding. It is not known if Tryptyr passes into breast milk. Tell your healthcare provider if you are breastfeeding or plan to breastfeed. Your healthcare provider will let you know if you should use Tryptyr while breastfeeding.

How can I get more information about Tryptyr?

For more information about Tryptyr, you can call the drugmaker at 800-757-9785.

Interactions

Does Tryptyr interact with foods or drinks?

There are no known interactions between Tryptyr and foods or drinks.

It is unknown if drinking alcohol will affect Tryptyr.

Does Tryptyr interact with other medicines (drug interactions)?

There are no known interactions between Tryptyr and other medicines. Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.