5 mins read

Overview: Clotic is an ear drop that is used for certain fungal ear infections. Make sure that you know how to use this medicine. This medicine may cause headaches. Try not to miss any doses, and finish your course even if you feel better. Tell your health care provider if your symptoms do not get better.

Uses

What is Clotic used for?

Clotic (clotrimazole) is commonly used for a fungal infection that affects your outer ear like your ear canal, called otomycosis.

Clotic may also be used for other conditions as determined by your health care provider.

How does Clotic work (mechanism of action)?

Clotic is an antifungal medicine that treats certain fungal infections by disrupting the fungi’s cell structure.

How is Clotic supplied (dosage forms)?

Clotic is available as a 1% ear drop (otic solution).

How should I store Clotic?

Clotic should be stored in the foil pouch (to protect from moisture) at room temperature, between 68 F and 77 F (20 C and 25 C). It can be exposed to temperatures between 59 F and 86 F (15 C and 30 C) for shorter periods of time, such as when transporting it. Store in a cool, dry place.

After opening a foil patch, remove a vial and use it right away. Keep unused vials in the foil pouch. Throw away any unused vials 30 days after you first open the foil pouch.

Side Effects

What are the most common side effects of Clotic?

The most common side effects of Clotic are listed below. Tell your health care provider if you have any of these side effects that bother you.

  • Headache
  • Ringing in your ears (tinnitus)
  • Tickling, tingling, or burning feeling 
  • Pain where the medicine is applied
  • Ruptured eardrum

There may be other side effects of Clotic that are not listed here. Contact your health care provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088 (800-332-1088). In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.

What are the serious side effects of Clotic?

While less common, the most serious side effects of Clotic are described below, along with what to do if they happen.

Severe Allergic Reactions. Clotic may cause allergic reactions, which can be serious. Stop using Clotic and get help right away if you have any of the following symptoms of a serious allergic reaction.

  • Breathing problems or wheezing
  • Racing heart
  • Fever or general ill feeling
  • Swollen lymph nodes
  • Swelling of the face, lips, mouth, tongue, or throat
  • Trouble swallowing or throat tightness
  • Itching or skin rash
  • Bumps on the skin called hives that can be red, pink, white, or brown depending on your skin tone
  • Nausea or vomiting
  • Dizziness, feeling lightheaded, or fainting
  • Stomach cramps
  • Joint pain

Warnings & Precautions

Who should not use Clotic?

Allergies to Ingredients. People who are allergic to any of the following should not use Clotic.

  • Clotic
  • Clotrimazole
  • Any of the ingredients in the specific product dispensed

Your pharmacist can tell you all of the ingredients in Clotic.

What should I know about Clotic before using it?

Do not use Clotic unless it has been prescribed to you by a health care provider. Use it as prescribed.

Do not share Clotic with other people, even if they have the same condition as you. It may harm them.

Keep Clotic out of the reach of children.

Right before using a vial, hold it between your hands for a minute or two. Doing so will warm the medicine, which may lower the risk of dizziness. Each vial is only for single-use. Throw away the vial as soon as you apply the medicine to your ear.

Make sure that you read the “Instructions for Use” that comes with your medicine. If you have any questions about how to use Clotic, talk with your health care provider.

Try to use this medicine every 12 hours. Consider setting a timer to help you remember when to use Clotic. 

What should I tell my health care provider before using Clotic?

Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them know if Clotic is right for you.

In particular, make sure that you discuss any of the following.

Pregnancy. It is not known if or how Clotic could affect pregnancy or harm an unborn baby. The amount of Clotic absorbed by the body is low and not expected to reach the baby. Tell your health care provider if you are pregnant or plan to become pregnant. Your health care provider will let you know if you should use Clotic while you are pregnant or trying to get pregnant. 

Breastfeeding. It is not known if Clotic passes into breast milk. The amount of Clotic absorbed by the body is low and breastfeeding is not expected to expose the child to the medicine. Tell your health care provider if you are breastfeeding or plan to breastfeed. Your health care provider will let you know if you should use Clotic while breastfeeding.

How can I get more information about Clotic?

For more information about Clotic, you can call the drugmaker at 954-218-1570.

Interactions

Does Clotic interact with foods or drinks?

There are no known interactions between Clotic and foods or drinks.

Does Clotic interact with other medicines (drug interactions)?

There are no known interactions between Clotic and other medicines. Always tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.

Does interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose/Missed Dose

What should I do if I accidentally use too much Clotic?

If you or someone else has used too much Clotic, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.

What should I do if I miss a dose of Clotic?

If you miss a dose, use it as soon as you remember. If it is almost time for your next dose, skip the missed dose and only use the next dose. Do not use double or extra doses. 

It is important to complete your prescribed course of Clotic, even if your symptoms get better or go away. This will reduce the risk that future infections are resistant to Clotic or other similar medicines.

Missing doses of Clotic can cause it to not work as well over time. So it is important not to miss or skip doses.