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Overview: Eraxis is an intravenous (IV) medicine used to treat certain fungal infections. Common side effects include nausea, vomiting, diarrhea, and fever. Serious side effects are less common and may include liver damage and infusion reactions. Notify your health care provider right away if you develop a rash or feel unusually weak or tired while using Eraxis.

Uses

What is Eraxis used for?

Eraxis (anidulafungin) is an antifungal medicine commonly used to treat certain candida fungal infections (candidiasis), including infections in your blood, belly, or throat.

Eraxis may also be used for other conditions as determined by your health care provider.

Eraxis may not be right for some of the infections listed above, depending on which germs are causing the infection. Fungi in some locations may have developed resistance to anidulafungin, which will make it not work as well.

How does Eraxis work (mechanism of action)?

Eraxis is an antifungal medicine that kills certain types of fungi by disrupting their cell structure.

How is Eraxis supplied (dosage forms)?

Brands and other names

  • Eraxis

Dosage forms and strengths

Eraxis is available in an injectable form that is given by a health care provider.

How should I store Eraxis?

Eraxis is usually given by a health care provider in a hospital or clinic. If you will store Eraxis at home, follow the instructions given by your health care provider.

Side Effects

What are the most common side effects of Eraxis?

The most common side effects of Eraxis are listed below. These side effects may vary depending on the condition that is being treated and the age of the person using the medicine. Tell your health care provider if you have any of these side effects that bother you.

  • Nausea, vomiting, diarrhea, upset stomach, or stomach pain
  • Fever
  • Trouble sleeping
  • Low blood pressure
  • Blood disorders, including low levels of platelets and red blood cells
  • Headache
  • Fungal infection in the mouth
  • Low levels of blood sugar and potassium
  • Nosebleeds
  • Rash
  • Abnormal liver function tests

There may be other side effects of Eraxis that are not listed here. Contact your health care provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088 (800-332-1088). In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.

What are the serious side effects of Eraxis?

While less common, the most serious side effects of Eraxis are described below, along with what to do if they happen.

Severe Allergic Reactions. Eraxis may cause allergic reactions, which can be serious. Stop using Eraxis and get help right away if you have any of the following symptoms of a serious allergic reaction.

  • Breathing problems or wheezing
  • Racing heart
  • Fever or general ill feeling
  • Swollen lymph nodes
  • Swelling of the face, lips, mouth, tongue, or throat
  • Trouble swallowing or throat tightness
  • Itching, skin rash, or pale red bumps on the skin called hives
  • Nausea or vomiting
  • Dizziness, feeling lightheaded, or fainting
  • Stomach cramps
  • Joint pain

Liver Damage. Liver damage, also called hepatotoxicity, can happen when using Eraxis. Keep all appointments, including those for lab tests, while you are using Eraxis. Call your health care provider right away if you have any of the following symptoms of liver damage.

  • Nausea or vomiting
  • Stomach or belly pain
  • Fever
  • Weakness or unusual tiredness
  • Itching
  • Loss of appetite
  • Light-colored poop
  • Dark-colored urine (pee)
  • Your skin or the whites of your eyes turning yellowish in color (also called jaundice)

Infusion Reactions. Eraxis can cause reactions that can be serious when it is given to you. Your infusion may need to be slowed or stopped if you have these reactions. Tell your health care provider right away if you have any of the following symptoms when you get your infusion.

  • Rash
  • Hives
  • Flushing
  • Itching
  • Difficulty breathing
  • Low blood pressure

Warnings & Precautions

Who should not use Eraxis?

Allergies to Ingredients. People who are allergic to any of the following should not use Eraxis.

  • Anidulafungin
  • Eraxis
  • Any other medicine known as an echinocandin
  • Any of the ingredients in the specific product dispensed

Your pharmacist can tell you all of the ingredients in Eraxis.

Hereditary Fructose Intolerance (HFI). People with a genetic condition called HFI should not use Eraxis. Eraxis contains fructose, which may cause dangerous side effects in people with HFI. Tell your health care provider if you have symptoms such as nausea, vomiting, or stomach pain after eating any type of sugar.

What should I know about Eraxis before using it?

Eraxis is usually given by a health care provider in a hospital or clinic. 

What should I tell my health care provider before using Eraxis?

Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if Eraxis is right for you.

In particular, make sure that you discuss any of the following.

Pregnancy. Eraxis may cause harm to a fetus. Tell your health care provider if you think you are pregnant or plan to become pregnant.

Breastfeeding. It is not known if Eraxis passes into breast milk. Tell your health care provider if you are breastfeeding or plan to breastfeed. Your health care provider will let you know if you should use Eraxis while breastfeeding.

How can I get more information about Eraxis?

For more information about Eraxis, you can visit the drugmaker’s website at www.pfizermedicalinformation.com or call them at 800-438-1985.

Interactions

Does Eraxis interact with foods or drinks?

There are no known interactions between Eraxis and foods or drinks.

It is unknown if drinking alcohol will affect Eraxis, but heavy drinking can slow your immune response and make it harder for your body to fight infection.

Does Eraxis interact with other medicines (drug interactions)?

There are no known interactions between Eraxis and other medicines. Always tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.

Does interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose/Missed Dose

What should I do if I accidentally use too much Eraxis?

If you or someone else has used too much Eraxis, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.

What should I do if I miss a dose of Eraxis?

Eraxis is usually given by a health care provider in a hospital or clinic. Your health care provider will make sure you are receiving Eraxis as scheduled. If you miss an appointment to get your Eraxis dose, call to make another appointment as soon as possible.