Pepcid Products for Heartburn and Upset Stomach

Medically Reviewed by Beth Johnston, PharmD, BCPS on March 19, 2025
2 min read

Pepcid products are commonly used to prevent and treat heartburn caused by acid indigestion and upset stomach. The main active ingredient in Pepcid is famotidine, which belongs to a class of medicines known as H2 blockers. Famotidine works by reducing the amount of acid made in the stomach, helping relieve symptoms caused by too much stomach acid. These products start to relieve heartburn within 15 to 30 minutes.

Pepcid Complete products also contain the antacids calcium carbonate and magnesium hydroxide. The addition of the antacid helps give faster relief from heartburn symptoms because the antacids start to neutralize stomach acid within seconds.

You can take Pepcid products with or without food. If you are using it to prevent symptoms, take it 10 to 60 minutes before foods or drinks that give you heartburn.

Pepcid products may be used for adults and children as young as 12 years old.

Do not take Pepcid products if you have trouble swallowing food, vomit with blood, or have black or tarry poop. These may be signs of a more serious condition and you should see a healthcare provider.

Symptoms of a heart attack may be mistaken for heartburn. Consult a healthcare provider if you have any of the following symptoms.

  • Chest pain or pressure
  • Fast or abnormal heartbeat
  • Trouble breathing
  • Pain in your back, jaw, throat, or arm
  • Sweating, upset stomach, vomiting, or dizziness

If you have kidney problems, you may not be able to metabolize Pepcid products properly. This can lead to higher than normal levels of the medicine in your blood and an increased risk of side effects including confusion, feeling uneasy or disoriented, trouble thinking clearly, hallucinations, seizures, and tiredness. A healthcare provider can help you determine which product and dose is safe for you. 

There may be side effects, additional warnings, and interactions with other medicines that are not listed here. These may vary depending on the combination of ingredients in the specific Pepcid product you are using. Always check the label before taking any Pepcid product. Talk to a pharmacist or healthcare provider about your health conditions and other medicines to help determine which Pepcid products are safe for you.

Use the table(s) below to help you find the best product to treat your symptoms

ProductOriginal Strength Pepcid AC
IngredientsFamotidine 10 mg
UsesHeartburn prevention and symptom relief
Dosage FormsOral tablets
ProductMaximum Strength Pepcid AC
IngredientsFamotidine 20 mg
UsesHeartburn prevention and symptom relief
Dosage FormsOral tablets
ProductPepcid Complete
Pepcid Complete ON-THE-GO
 
IngredientsFamotidine 10 mg
Calcium carbonate 800 mg
Magnesium hydroxide 165 mg
UsesHeartburn symptom relief
Dosage FormsChewable tablets