Medically Reviewed by Poonam Sachdev on October 04, 2024
What Is Depo-Provera?
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What Is Depo-Provera?

Depo-Provera is birth control method you can get as a shot. It's a man-made hormone, medroxyprogesterone, which is similar to the natural hormone progesterone

How Does It Work?
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How Does It Work?

Depo-Provera stops the ovaries from releasing eggs and alters the uterine lining and cervical mucus to keep sperm from reaching any eggs.

How to Use
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How to Use

You'll have to get a shot every 12 weeks to get full protection. After your first injection, doctors recommend using backup birth control, such as a condom, for the first 7 days.

Common Side Effects
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Common Side Effects

Changes to your menstrual cycle are the most common side effects. After a year of use, about 50% of women will stop getting their periods. Other common side effects include headaches, weight gain, and acne.

Bone Mineral Density Concerns
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Bone Mineral Density Concerns

Long-term use of Depo-Provera may lead you to lose bone mineral density, which makes you more likely to get osteoporosis. Your chances are higher if you've taken the shot for longer than 2 years, especially if osteoporosis runs in your family, if you drink a lot, if you smoke, or if you have other risk factors for the condition.

Who Should Not Use Depo-Provera?
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Who Should Not Use Depo-Provera?

People with certain medical conditions should avoid using Depo-Provera. These include liver disease, breast cancer, and blood clots.

STD Protection
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STD Protection

Depo-Provera does not protect against sexually transmitted diseases (STDs). If you are at risk of STDs, consider using additional protection, such as condoms.

This content was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.