Remedies for Eczema

Written by WebMD Editorial Contributor, Felicia Wilson
Medically Reviewed by Stephanie S. Gardner, MD on June 20, 2025
5 min read

Eczema is a dry, itchy, red skin rash. If you have it, your outermost skin layer is disrupted, making you more sensitive to environmental allergens and an raising the risk of infection.  

While it’s not contagious, eczema can become a persistent and frustrating problem. Symptoms include:

  • Dry, itchy skin
  • Red and brown or gray patches that appear on the hands, wrists, ankles, feet, insides of the elbows, and on the backs of the knees
  • Small raised bumps that leak fluid and become crusty when scratched 
  • Inflamed patches of skin
  • Thick, swollen, or scaly skin

Nearly 15 million Americans have some form of eczema. Men and women are equally affected, but it is more common in people who have a family history of food and environmental allergies or asthma. The most common form of eczema is atopic dermatitis.

There is no permanent cure for eczema, but certain lifestyle changes and treatments may ease itching and prevent future breakouts.

Clean and Healthy Habits

If you have a history of eczema flare-ups, a consistent home routine can help. Do any or all of the following:

  • Use soap-free, oil-free, and unscented hair and body products, and fragrance-free laundry products. Avoid scented air fresheners and candles as well.
  • Drink plenty of water to keep your skin hydrated.
  • Clean your house regularly to get rid of allergens like pollen, mold, and tobacco smoke. 
  • Avoid stress that can lead to flare-ups by incorporating exercise, meditation, or counseling into your daily and weekly schedule.
  • Take cool, short (under 10 minutes) showers, and seal in moisture with a fragrance-free moisturizer.

It’s also a good idea to remove anything that may irritate your skin from your environment – like certain lotions, soaps, and fabrics. If you’re allergic to food items or fur from particular animals, avoid those, too.

Oral and Topical Medication

Many over-the-counter (OTC) and prescription treatments are available for people with eczema. You may work with your doctor and try several options to find the best medications for your skin. A health care professional may recommend one or more of the following:

  • Antihistamines: These block histamines, which cause allergy symptoms, like redness and itching. They are effective but may cause you to feel tired. 
  • Antibiotics: Scratching your skin can introduce bacteria and cause a skin infection. Oral antibiotics get rid of this bacteria and can ease eczema symptoms. Take the entire course of antibiotics. 
  • Biologics: These drugs block the source of inflammation that causes eczema. There are four biologics approved for eczema. They are dupilumab (Dupixent), lebrikizumab (Ebglyss), nemolizumab (Nemluvio), and tralokinumab (Adbry).
  • Calcineurin Inhibitors: These are immunosuppressant drugs that lead to a reduction in inflammation in conditions like eczema and rheumatoid arthritis. For eczema, they include pimecrolimus (Elidel) and tacrolimus (Protopic).
  • Corticosteroids: Prescription pills, creams, ointments, or shots that are used for more severe cases. This steroid type has serious side effects when used for long periods and is usually only used to stop a flare-up.
  • Cyclosporine: A medication that suppresses the immune system to prevent flare-ups. It can be taken as a pill or liquid. Talk to your doctor about potential side effects. 
  • JAK Inhibitors: These oral and topical drugs – abrocitinib (Cibinqo), ruxolitinib (Opzelura), and upadacitinib (Rinvoq) – are used to treat chronic inflammatory disorders like atopic dermatitis. They work by suppressing enzymes that promote inflammation.
  • Methotrexate: This treatment is also an immunomodulator/immunosuppressant that can help manage eczema. But there is evidence it can harm the liver if used for long periods. 
  • Phosphodiesterase 4 (PDE-4 inhibitors): These are drugs that suppress inflammation. These are FDA-approved for eczema: Zoryve cream and Eucrisa ointment.
  • Phototherapy: Light therapy relies on specific wavelengths of ultraviolet (UV) light to target the immune system and stop inflammation. 
  • Topical steroid creams: An ointment or cream applied directly to the affected area to ease inflammation and swelling. Steroid creams, ointments, foams, lotions, and solutions come in different strengths. Overusing them can lead to discoloration and thinning of the skin.
  • AhR agonists. AhR is short for aryl hydrocarbon receptor. It can help to lower inflammation by activating AhR along with proteins that may help your skin barrier work better. The AhR agonist tapinarof (Vtama) is approved for moderate to severe atopic dermatitis, which may include hand eczema. Studies have shown it can help clear your skin and ease itching.

Eczema symptoms range from mild to severe and make you more prone to skin infections. See a doctor if you or your child is having:

  • Discomfort and pain that keeps you from sleeping or functioning normally
  • Excessive eczema symptoms even after trying over-the-counter or home treatments
  • Worsening skin infections – especially if they include pus, red streaks, or yellow scabs

If any or all of these symptoms come with a fever, seek medical attention right away.

About 10% to 20% of infants get eczema, with the rash typically appearing on the face and scalp. In most cases, this condition improves after age 5 and may disappear for good.

Medical experts believe it’s a genetic condition or passed from parents to their kids. Symptoms can vary depending on the age of the child. 

In more severe cases, infants can get eczema on uncommon areas like the torso, elbows, and knees. Children and teens will notice the rash in the inner elbows, behind the knees, on the neck, or on the wrists and ankles. The skin may appear drier, thicker, and develop a scaly texture. 

There are some steps you can take to treat your child's eczema or prevent future flare-ups: 

  • Avoid skin care products with heavy fragrances and other possible irritants.
  • Cut your child’s fingernails and encourage them to wear gloves to prevent skin damage from scratching.
  • Maintain a routine of bathing, moisturizing, and applying age-appropriate treatments recommended by a pediatrician. Ask your doctor about the “soak and seal” method. Bathing less often will help preserve natural skin oils.
  • Talk to a pediatrician or dermatologist about the benefits of oatmeal baths or bleach baths to reduce inflammation and discourage bacterial growth.
  • Make topical medication work better and rehydrate the skin by using wet wrap therapy. This can also prevent your child from scratching their skin.