Foods That May Reduce Endometrial Cancer Risk

Endometrial Cancer Diet: How to Reduce Your Risk
While you may not have control over certain risk factors for endometrial cancer, you do have power over what you eat. Nutrients in a variety of foods may help you lower your risk by as much as 50%. Include these nutrients in your daily diet:
- Glucosinolates
- Antioxidants
- Ellagic acid
- Dietary fiber
- Phytoestrogens
- Omega-3 fatty acids
Crunch Cruciferous Vegetables
Eating cruciferous vegetables (like broccoli, cauliflower, Brussels sprouts, kale, bok choy, and collard and mustard greens) on a regular basis may lower your risk of endometrial cancer by up to 20%. They're filled with glucosinolates – plant compounds that can block cancer cells and prevent the growth and spread of tumors. Other compounds in these vegetables may help break down and clear hormones like estrogen. Having high levels of estrogen raises your risk of endometrial cancer.
Load Up on Berries
Antioxidants can help your body fight free radicals (chemicals that can harm your cells). Your body makes some antioxidants, but not enough. Berries are full of these, including vitamin C, anthocyanins, and ellagic acid. By getting antioxidants from whole foods, you also get fiber and other vitamins and minerals that are good for your health. Add a serving (about half a cup) of fresh or frozen blueberries, strawberries, raspberries, or blackberries to a smoothie, oatmeal, or salad.
Swap In Whole Grains
A diet high in fiber may lower your risk of endometrial cancer by as much as 46%. This is a great reason to eat whole grains including oats, brown rice, popcorn, and bulgur, which contains the most fiber of any whole grain. Fiber from whole grains helps absorb and regulate your estrogen levels. It can also help you lose weight, an important part of endometrial cancer prevention.
Aim for 3-6 ounces (one slice of bread or a half-cup of rice) of total grains daily. Make at least half of those whole grains.
Say Hello to Soy
Research shows that adding soy products to your diet may reduce endometrial cancer risk by 20%-26%. Foods like tofu, tempeh, edamame, soy milk, and yogurt contain phytoestrogens, which can lower blood estrogen by blocking testosterone from converting into estrogen and binding to estrogen receptors. While soy is healthy, eat it in moderation. Too much can increase estrogen. The FDA recommends 25 grams daily. Talk to your doctor if you have health conditions like hypothyroidism, a soy allergy, kidney disease, or have had breast or uterine cancer before increasing soy intake.
Fish for Good Health
Omega-3 fatty acids help your cells function. But we can’t make enough of it by ourselves, so we have to get some from food. They're found in fish including salmon, mackerel, white fish, and tuna. You can also get omega-3s from plant-based products like ground flaxseeds, walnuts, and soybean and canola oils. Eating foods with omega-3 fatty acids has been shown to lower inflammation in your body, which is linked to cancer in many ways. You don’t need a lot of omega-3 fatty acids to benefit your health. Experts suggest around 1.5 grams each day (about half an ounce of walnuts) or two 3- to 4-ounce servings of fatty fish each week.
SOURCES:
Physicians Committee for Responsible Medicine: “Nutrition Guide for Clinicians.”
Frontiers in Nutrition: “Metabolic Fate of Dietary Glucosinolates and Their Metabolites: A Role for the Microbiome,” “Increased Dietary Fiber is Associated with Weight Loss Among Full Plate Living Program Participants.”
Mayo Clinic: “Dietary Fiber: Essential for a Healthy Diet.”
Whole Health Library: “Phytoestrogens.”
Advances in Nutrition: “Recent Research on the Health Benefits of Blueberries and Their Anthocyanins.”
Nutrition: “Edible Berries: Bioactive Components and Their Effect on Human Health.”
Cleveland Clinic: “Omega-3 Fatty Acids,” “Oxidative Stress.”
Nutrition and Cancer: “Fruits and Vegetables and Endometrial Cancer Risk: A Systematic Literature Review and Meta-Analysis.”
American Journal of Epidemiology: “A Prospective Study of Fruits, Vegetables, and Risk of Endometrial Cancer.”
Morbidity and Mortality Weekly Report: “Adults Meeting Fruit and Vegetable Intake Recommendations – United States, 2019.”
National Cancer Institute: “Antioxidants and Cancer Prevention.”
American Journal of Epidemiology: “Association of Soy and Fiber Consumption with the Risk of Endometrial Cancer.”
Oldways Whole Grains Council: “Fiber in Whole Grains.”
Harvard Health Publishing: “Making One Change – Getting More Fiber – Can Help With Weight Loss.”
Nutrients: “Effects of Dietary Phytoestrogens on Hormones Throughout a Human Lifespan: A Review.”
Mount Sinai: “Soy.”
Clinical Nutrition ESPEN: “Role of Omega-3 fatty acids eicosapentaenoic (EPA) and docosahexaenoic (DHA) as modulatory and anti-inflammatory agents in noncommunicable diet-related diseases – Reports from the last 10 years.”
City of Hope Cancer Center: “Does Inflammation Cause Cancer? Learn the Connection.”
American Heart Association: “Consuming About 3 Grams of Omega-3 Fatty Acids a Day May Lower Blood Pressure.”
California Walnuts: “Omega-3 ALA.”