PORIA MUSHROOM: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

Poria mushroom (Wolfiporia cocos) is a fungus. The spores, which store food for the fungus, are sometimes used to make medicine.

Poria mushroom contains chemicals that might reduce swelling and change immune function.

Poria mushroom has been used for memory, anxiety, fatigue, and many other conditions, but there is no good scientific evidence to support these uses. There is also no good evidence to support using poria mushroom for COVID-19.

Uses & Effectiveness

We currently have no information for PORIA MUSHROOM overview.

Side Effects

When taken by mouth: There isn't enough reliable information to know if poria mushroom is safe. It can sometimes cause allergic reactions.

Special Precautions and Warnings

When taken by mouth: There isn't enough reliable information to know if poria mushroom is safe. It can sometimes cause allergic reactions.

Pregnancy and breast-feeding: There isn't enough reliable information to know if poria mushroom is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Surgery: Poria mushroom might slow down the central nervous system (CNS). When combined with anesthesia and other medications used during and after surgery, this might slow down the CNS too much. Stop using poria mushroom as a medicine at least 2 weeks before a scheduled surgery.

Interactions

Moderate Interaction

Be cautious with this combination

Drying medications (Anticholinergic drugs) interacts with PORIA MUSHROOM
Poria mushroom essential oil might increase a chemical in the body called acetylcholine. Acetylcholine plays a big part in many important body functions. Some medications, called anticholinergic drugs, block the effects of acetylcholine in the body. Taking poria mushroom might decrease the effects of anticholinergic drugs.
Sedative medications (CNS depressants) interacts with PORIA MUSHROOM
Poria mushroom extract might cause sleepiness and slowed breathing. Some medications, called sedatives, can also cause sleepiness and slowed breathing. Taking poria mushroom extract with sedative medications might cause breathing problems and/or too much sleepiness.
Various medications used for glaucoma, Alzheimer disease, and other conditions (Cholinergic drugs) interacts with PORIA MUSHROOM
Poria mushroom essential oil might increase a chemical in the body called acetylcholine. Some medications that are used for glaucoma, Alzheimer disease, and other conditions, also increase acetylcholine levels. Taking poria mushroom with these medications might increase the chance of side effects.

Dosing

There isn't enough reliable information to know what an appropriate dose of poria mushroom might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.

View References

REFERENCES:

Kaminaga T, Yasukawa K, Kanno H, et al. Inhibitory effects of lanostane-type triterpene acids, the components of Poria cocos, on tumor promotion by 12-O tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin. Oncology 1996;53:382-5. View abstract.

Kim H, Park I, Park K, Park S, Kim YI, Park BG. The positive effects of Poria cocos extract on quality of sleep in insomnia rat models. Int J Environ Res Public Health 2022;19(11):6629. View abstract.

Lewis ED, Crowley DC, Guthrie N, Evans M. Healthy adults supplemented with a nutraceutical formulation containing Aloe vera gel, rosemary and Poria cocos enhances the effect of influenza vaccination in a randomized, triple-blind, placebo-controlled trial. Front Nutr. 2023;10:1116634. View abstract.

Li YL. [Clinical and experimental study on the treatment of children diarrhea by granule of children-diarrhea fast-stopping]. [Article in Chinese]. Chung Hsi I Chieh Ho Tsa Chih 1991;11:79-82, 67. View abstract.

Liu J, Liu L, Zhang G, Peng X. Poria cocos polysaccharides attenuate chronic nonbacterial prostatitis by targeting the gut microbiota: Comparative study of Poria cocos polysaccharides and finasteride in treating chronic prostatitis. Int J Biol Macromol 2021;189:346-355. View abstract.

Liu J, Yu J, Peng X. Poria cocos polysaccharides alleviates chronic nonbacterial prostatitis by preventing oxidative stress, regulating hormone production, modifying gut microbiota, and remodeling the DNA methylome. J Agric Food Chem 2020;68(45):12661-70. View abstract.

Lv Q, Di X, Bian B, Li K, Guo J. Neuroprotective effects of Poria cocos (Agaricomycetes) essential oil on Aß1-40-induced learning and memory deficit in rats. Int J Med Mushrooms 2022;24(10):73-82. View abstract.

Nukaya H, Yamashiro H, Fukazawa H, et al. Isolation of inhibitors of TPA-induced mouse ear edema from Hoelen, Poria cocos. Chem Pharm Bull (Tokyo) 1996;44:847-9. View abstract.

Prieto JM, Recio MC, Giner RM, et al. Influence of traditional Chinese anti-inflammatory medicinal plants on leukocyte and platelet functions. J Pharm Pharmacol 2003;55:1275-82. View abstract.

Ríos JL. Chemical constituents and pharmacological properties of Poria cocos. Planta Med. 2011 May;77(7):681-91. View abstract.

Sun Y. Biological activities and potential health benefits of polysaccharides from Poria cocos and their derivatives. Int J Biol Macromol. 2014 Jul;68:131-4. View abstract.

Tai T, Akita Y, Kinoshita K, et al. Anti-emetic principles of Poria cocos. Planta Med 1995;61:527-30. View abstract.

Tseng J, Chang JG. Suppression of tumor necrosis factor-alpha, interleukin-1 beta, interleukin-6 and granulocyte-monocyte colony stimulating factor secretion from human monocytes by an extract of Poria cocos. Chung Hua Min Kuo Wei Sheng Wu Chi Mien I Hsueh Tsa Chih 1992;25:1-11. View abstract.

Wang H, Luo Y, Chu Z, et al. Poria acid, triterpenoids extracted from Poria cocos, inhibits the invasion and metastasis of gastric cancer cells. Molecules 2022;27(11):3629. View abstract.

Wang SQ, Du XR, Lu HW, et al. Experimental and clinical studies of Shen Yan Ling in treatment of chronic glomerulonephritis. J Tradit Chin Med 1989;9:132-4. View abstract.

Wang SS, Yang S, Ma Y. [Efficacy of poria-polyporus anti-diarrhea oral liquor in treating infantile rotavirus diarrhea: a controlled study with smicta]. Chung Kuo Chung Hsi I Chieh Ho Tsa Chih 1995;15:284-6. View abstract.

Wei W, Shu S, Zhu W, Xiong Y, Peng F. The Kinome of Edible and Medicinal Fungus Wolfiporia cocos. Front Microbiol. 2016 Sep 21;7:1495. View abstract.

Xu H, Wang S, Jiang Y, et al. Poria cocos Polysaccharide ameliorated antibiotic-associated diarrhea in mice via regulating the homeostasis of the gut microbiota and intestinal mucosal barrier. Int J Mol Sci 2023;24(2):1423. View abstract.

Yang DJ. [Tinnitus treated with combined traditional Chinese medicine and Western medicine]. Chung Hsi I Chieh Ho Tsa Chih 1989;9:270-1, 259-60. View abstract.

Yasukawa K, Kaminaga T, Kitanaka S, et al. 3 beta-p-hydroxybenzoyldehydrotumulosic acid from Poria cocos, and its anti-inflammatory effect. Phytochemistry 1998;48:1357-60. View abstract.

Yi XL, Hu J, Wu QT, et al. Effect of different-volume fluid resuscitation on organ functions in severe acute pancreatitis and therapeutic effect of Poria cocos. Evid Based Complement Alternat Med 2020;2020:6408202. View abstract.

Zhang D, Li H, Luo X, Liu D, Wei Q, Ye X. Integrated 16S rDNA, metabolomics, and TNF-a/NF-?B signaling pathway analyses to explain the modulatory effect of Poria cocos aqueous extract on anxiety-like behavior. Phytomedicine 2022;104:154300. View abstract.

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

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PORIA MUSHROOM - Uses, Side Effects, and More