Grundy WE, Freed M, Johnson H.C., et al. The effect of phthalylsulfathiazole (sulfathalidine) on the excretion of B-vitamins by normal adults. Arch Biochem. 1947 Nov;15:187-94. View abstract.
Henry JG, Sobki S, Afafat N. Interference by biotin therapy on measurement of TSH and FT4 by enzyme immunoassay on Boehringer Mannheim ES 700 analyzer. Ann Clin Biochem 1996;33:162-3. View abstract.
Hill MJ. Intestinal flora and endogenous vitamin synthesis. Eur J Cancer Prev 1997;6:S43-5. View abstract.
Hochman LG, Scher RK, Meyerson MS. Brittle nails: response to daily biotin supplementation. Cutis 1993;51:303-5. View abstract.
James A, Stalan J, Kuzhively J. Biotin induced biochemical hyperthyroidism: a case report and review of the literature. J Med Case Rep 2023;17(1):266. View abstract.
Juntas-Morales R, Pageot N, Bendarraz A, et al. High-dose pharmaceutical grade biotin (MD1003) in amyotrophic lateral sclerosis: A pilot study. EClinicalMedicine. 2020;19:100254. View abstract.
Keipert JA. Oral use of biotin in seborrhoeic dermatitis of infancy: a controlled trial. Med J Aust 1976;1:584-5. View abstract.
Kodani M, Poe A, Drobeniuc J, Mixson-Hayden T. Determination of potential biotin interference on accuracy of results of serologic assays for various viral hepatitis markers. J Med Virol. View abstract.
Koutsikos D, Agroyannis B, Tzanatos-Exarchou H. Biotin for diabetic peripheral neuropathy. Biomed Pharmacother 1990;44:511-4. View abstract.
Krause KH, Berlit P, Bonjour JP. Vitamin status in patients on chronic anticonvulsant therapy. Int J Vitam Nutr Res 1982;52:375-85. View abstract.
Krause KH, Bonjour JP, Berlit P, Kochen W. Biotin status of epileptics. Ann N Y Acad Sci 1985;447:297-313. View abstract.
Krause KH, Kochen W, Berlit P, Bonjour JP. Excretion of organic acids associated with biotin deficiency in chronic anticonvulsant therapy. Int J Vitam Nutr Res 1984;54:217-22. View abstract.
Kummer S, Hermsen D, Distelmaier F. Biotin treatment mimicking Graves' disease. N Engl J Med 2016;375(7):704-6. View abstract.
Kwok JS, Chan IH, Chan MH. Biotin interference on TSH and free thyroid hormone measurement. Pathology. 2012;44(3):278-80. View abstract.
Li D, Ferguson A, Cervinski MA, Lynch KL, Kyle PB. AACC Guidance Document on Biotin Interference in Laboratory Tests. J Appl Lab Med. 2020;5(3):575-587. View abstract.
Lininger SW. The Natural Pharmacy. 1st ed. Rocklin, CA: Prima Publishing; 1998.
Mathais S, Moisset X, Pereira B, et al. Relapses in patients treated with high-dose biotin for progressive multiple sclerosis. Neurotherapeutics. 2020 Sep 22. View abstract.
Minkovsky A, Lee MN, Dowlatshahi M, et al. High-dose biotin treatment for secondary progressive multiple sclerosis may interfere with thyroid assays. AACE Clin Case Rep 2016;2(4):e370-e373. View abstract.
Mock DM, Dyken ME. Biotin catabolism is accelerated in adults receiving long-term therapy with anticonvulsants. Neurology 1997;49:1444-7. View abstract.
Mock DM, Dyken ME. Biotin deficiency results from long-term therapy with anticonvulsants (abstract). Gastroenterology 1995;108:A740.
Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. View abstract.
Mock NI, Malik MI, Stumbo PJ, et al. Increased urinary excretion of 3-hydroxyisovaleric acid and decreased urinary excretion of biotin are sensitive early indicators of decreased status in experimental biotin deficiency. Am J Clin Nutr 1997;65:951-8. View abstract.
Oguma S, Ando I, Hirose T, et al. Biotin ameliorates muscle cramps of hemodialysis patients: a prospective trial. Tohoku J Exp Med 2012;227(3):217-23. View abstract.
Pacheco-Alvarez D, Solórzano-Vargas RS, Del Río AL. Biotin in Metabolism and Its Relationship to Human Disease. Arch Med Res 2002;33(5):439-47. View abstract.
Piketty ML, Prie D, Sedel F, et al. High-dose biotin therapy leading to false biochemical endocrine profiles: validation of a simple method to overcome biotin interference. Clin Chem Lab Med 2017;55(6):817-25. View abstract.
Bhatti RA, Ablin RJ, and Guinan PD. Tumour-associated directed immunity in prostatic cancer: effect of amygdalin. IRCS Med Sci 1981;9(1):19.
Biaglow, J. E. and Durand, R. E. The enhanced radiation response of an in vitro tumour model by cyanide released from hydrolysed amygdalin. Int J Radiat Biol Relat Stud.Phys Chem Med 1978;33(4):397-401. View abstract.
Brown WE, Wood CD, and Smith AN. Sodium cyanide as a cancer chemotherapeutic agent: laboratory and clinical studies. Amer J Obstet Gyn 1960;80(5):907-918.
Gostomski FE. The effects of amygdalin on the Krebs-2 carcinoma in adult and fetal DUB (ICR) mice. Disseration Abstracts International 1978;39(5):2075-B.
Hill, G. J., Shine, T. E., Hill, H. Z., and Miller, C. Failure of amygdalin to arrest B16 melanoma and BW5147 AKR leukemia. Cancer Res 1976;36(6):2102-2107. View abstract.
Khandekar, J. D. and Edelman, H. Studies of amygdalin (laetrile) toxicity in rodents. JAMA 7-13-1979;242(2):169-171. View abstract.
Laster, W. R., Jr. and Schabel, F. M., Jr. Experimental studies of the antitumor activity of amygdalin MF (NSC- 15780) alone and in combination with beta-glucosidase (NSC-128056). Cancer Chemother Rep 1975;59(5):951-965. View abstract.
Lea, M. A. and Koch, M. R. Effects of cyanate, thiocyanate, and amygdalin on metabolite uptake in normal and neoplastic tissues of the rat. J Natl.Cancer Inst. 1979;63(5):1279-1283. View abstract.
Manner HW, DiSanti SJ, Maggio MI, and et al. Amygdalin, vitamin A and enzyme induced regression of murine mammary adenocarcinomas. J Manip Physiol Ther 1978;1(4):246-248.
Milazzo, S., Ernst, E., Lejeune, S., and Schmidt, K. Laetrile treatment for cancer. Cochrane.Database.Syst.Rev 2006;(2):CD005476. View abstract.
Moertel, C. G., Ames, M. M., Kovach, J. S., Moyer, T. P., Rubin, J. R., and Tinker, J. H. A pharmacologic and toxicological study of amygdalin. JAMA 2-13-1981;245(6):591-594. View abstract.
Moertel, C. G., Fleming, T. R., Rubin, J., Kvols, L. K., Sarna, G., Koch, R., Currie, V. E., Young, C. W., Jones, S. E., and Davignon, J. P. A clinical trial of amygdalin (Laetrile) in the treatment of human cancer. N.Engl.J.Med. 1-28-1982;306(4):201-206. View abstract.
Morrone JA. Chemotherapy of inoperable cancer: preliminary report of 10 cases treated with laetrile. J Exper Med Surg 1962;20:299-308.
Navarro MD. Five years experience with laetrile therapy in advanced cancer. Acta Unio Internat Contra Cancrum 1959;15(suppl 1):209-221.
Navarro MD. The Philippine experience in the early detection and chemotherapy of cancer. Santo Tomas J Med 1970;25(3):125-133.
Ovejera, A. A., Houchens, D. P., Barker, A. D., and Venditti, J. M. Inactivity of DL-amygdalin against human breast and colon tumor xenografts in athymic (nude) mice. Cancer Treat.Rep 1978;62(4):576-578. View abstract.
Ross, W. E. Unconventional cancer therapy. Compr.Ther 1985;11(9):37-43. View abstract.
Stock, C. C., Tarnowski, G. S., Schmid, F. A., Hutchison, D. J., and Teller, M. N. Antitumor tests of amygdalin in transplantable animal tumor systems. J Surg Oncol 1978;10(2):81-88. View abstract.
Syrigos, K. N., Rowlinson-Busza, G., and Epenetos, A. A. In vitro cytotoxicity following specific activation of amygdalin by beta-glucosidase conjugated to a bladder cancer-associated monoclonal antibody. Int J Cancer 12-9-1998;78(6):712-719. View abstract.
Wodinsky, I. and Swiniarski, J. K. Antitumor activity of amygdalin MF (NSC-15780) as a single agent and with beta-glucosidase (NSC-128056) on a spectrum of transplantable rodent tumors. Cancer Chemother Rep 1975;59(5):939-950. View abstract.
Chen J, Liu L, Li M, Yu X, Zhang R. An improved method for determination of cyanide content in bitter almond oil. J Oleo Sci. 2018;67(3):289-294. View abstract.
Food and Drug Administration. Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA); Public Law 108-282, Title II. Accessed on May 19, 2021. Available at: https://www.fda.gov/food/food-allergensgluten-free-guidance-documents-regulatory-information/food-allergen-labeling-and-consumer-protection-act-2004-falcpa.
Polk BI, Dinakarpandian D, Nanda M, Barnes C, Dinakar C. Association of tree nut and coconut sensitizations. Ann Allergy Asthma Immunol. 2016;117(4):412-416. View abstract.
Randhawa I, Morphew T, Marsteller NL. Correlation of negative skin-prick test results for tree nuts and successful tree nut challenges among children with peanut allergy. Allergy Asthma Proc. 2018;39(6):456-460. View abstract.
Select a condition to view a list of vitamins
CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.
This copyrighted material is licensed from Therapeutic Research Center, LLC. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
Licensed from Therapeutic Research Center, LLC
Copyright © 1995-2024 by Therapeutic Research Center, LLC. All Rights Reserved.