QUINCE: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

Quince (Cydonia oblonga) is a tree with a hard yellow fruit. The fruit is eaten in jams and baked goods. The fruit and leaves have been used as medicine.

Some chemicals in quince might change how the immune system responds to substances that cause allergic reactions.

Quince is used for persistent heartburn in children. Quince is also used for morning sickness, hay fever, stomach ulcers, and many other conditions, but there is no good scientific evidence to support these other uses.

Uses & Effectiveness

Possibly Effective for

Persistent heartburn. In children and teens, taking quince fruit syrup twice daily seems to reduce symptoms of persistent heartburn by a small amount.

There is interest in using quince for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.

Side Effects

When taken by mouth: Quince fruit is commonly consumed in foods. But there isn't enough reliable information to know if quince fruit is safe when used in larger amounts as medicine.

When applied to the skin: There isn't enough reliable information to know if quince is safe or what the side effects might be.

Special Precautions and Warnings

Pregnancy and breast-feeding: Quince fruit is commonly consumed in foods. There isn't enough reliable information to know if quince fruit is safe to use in larger amounts as medicine when pregnant or breast-feeding. Stay on the safe side and stick to food amounts.

Interactions

We currently have no information for QUINCE overview.

Dosing

Quince fruit is often used in baked goods, jams, and marmalades. As a medicine, there isn't enough reliable information to know what an appropriate dose of quince might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.

View References

REFERENCES:

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Jiang W, Wang X, Xu X, Kong L. Effect of Schisandra sphenanthera extract on the concentration of tacrolimus in the blood of liver transplant patients. Int J Clin Pharmacol Ther. 2010 Mar;48(3):224-9. View abstract.

Karosanidze I, Kiladze U, Kirtadze N, et al. Efficacy of adaptogens in patients with long COVID-19: a randomized, quadruple-blind, placebo-controlled trial. Pharmaceuticals (Basel) 2022;15(3):345. View abstract.

Kim DS, Baek HI, Ha KC, Cha YS, Park SJ. Efficacy and Safety of Omija (Schisandra chinensis) Extract Mixture on the Improvement of Hyperglycemia: A Randomized, Double-Blind, and Placebo-Controlled Clinical Trial. Nutrients 2022;14(15):3159. View abstract.

Kou K, Sun X, Li M, et al. Beneficial effects of Wuzhi capsule on tacrolimus blood concentrations in liver transplant patients with different donor-recipient CYP3A5 genotypes. J Clin Pharm Ther 2022;47(2):200-10. View abstract.

Baars EW, Savelkoul HF. Citrus/Cydonia comp. can restore the immunological balance in seasonal allergic rhinitis-related immunological parameters in vitro. Mediators Inflamm. 2008;2008:496467. View abstract.

Costa RM, Magalhães AS, Pereira JA, et al. Evaluation of free radical-scavenging and antihemolytic activities of quince (Cydonia oblonga) leaf: a comparative study with green tea (Camellia sinensis). Food Chem Toxicol. 2009;47(4):860-5. View abstract.

Essafi-Benkhadir K, Refai A, Riahi I, Fattouch S, Karoui H, Essafi M. Quince (Cydonia oblonga Miller) peel polyphenols modulate LPS-induced inflammation in human THP-1-derived macrophages through NF-?B, p38MAPK and Akt inhibition. Biochem Biophys Res Commun. 2012;418(1):180-5. View abstract.

Gründemann C, Papagiannopoulos M, Lamy E, Mersch-Sundermann V, Huber R. Immunomodulatory properties of a lemon-quince preparation (Gencydo®) as an indicator of anti-allergic potency. Phytomedicine. 2011;18(8-9):760-8. View abstract.

Hoffmann A, Klein SD, Gründemann C, Garcia-Käufer M, Wolf U, Huber R. Efficacy of a nasal spray from Citrus limon and Cydonia oblonga for the treatment of hay fever symptoms-A randomized, placebo controlled cross-over study. Phytother Res. 2016;30(9):1481-6. View abstract.

Huber R, Stintzing FC, Briemle D, Beckmann C, Meyer U, Gründemann C. In vitro antiallergic effects of aqueous fermented preparations from Citrus and Cydonia fruits. Planta Med. 2012;78(4):334-40. View abstract.

Jafari-Dehkordi E, Hashem-Dabaghian F, Aliasl F, et al. Comparison of quince with vitamin B6 for treatment of nausea and vomiting in pregnancy: a randomised clinical trial. J Obstet Gynaecol. 2017;37(8):1048-1052. View abstract.

Kawahara T, Tsutsui K, Nakanishi E, Inoue T, Hamauzu Y. Effect of the topical application of an ethanol extract of quince seeds on the development of atopic dermatitis-like symptoms in NC/Nga mice. BMC Complement Altern Med. 2017;17(1):80. View abstract.

Naeimi M, Kianifar H, Memariani Z, et al. Comparison of the efficacy of ranitidine and quince syrup on gastroesophageal reflux disease in children. Complement Ther Med 2019;45:215-21. View abstract.

Pacifico S, Gallicchio M, Fiorentino A, Fischer A, Meyer U, Stintzing FC. Antioxidant properties and cytotoxic effects on human cancer cell lines of aqueous fermented and lipophilic quince (Cydonia oblonga Mill.) preparations. Food Chem Toxicol. 2012;50(11):4130-5. View abstract.

Shinomiya F, Hamauzu Y, Kawahara T. Anti-allergic effect of a hot-water extract of quince (Cydonia oblonga). Biosci Biotechnol Biochem. 2009;73(8):1773-8. View abstract.

Zohalinezhad ME, Imanieh MH, Samani SM, et al. Effects of Quince syrup on clinical symptoms of children with symptomatic gastroesophageal reflux disease: A double-blind randomized controlled clinical trial. Complement Ther Clin Pract. 2015;21(4):268-76. View abstract.

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

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