CATUABA: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

Catuaba is an herb. People use the bark to make medicine.

People use catuaba for sexual arousal and performance, agitation, poor memory, and many other conditions, but there is no good scientific evidence to support these uses.

How does it work ?

Catuaba contains chemicals that might work against certain bacteria and viruses.

Uses & Effectiveness

Insufficient Evidence for

Male sexual performance problems.
Anxiety.
Exhaustion.
Fatigue.
Sleeplessness.
Nervousness.
Poor memory or forgetfulness.
Skin cancer.
Other conditions.

More evidence is needed to rate the effectiveness of catuaba for these uses.

Side Effects

When taken by mouth: There isn't enough reliable information to know if catuaba is safe or what the side effects might be.

Special Precautions and Warnings

When taken by mouth: There isn't enough reliable information to know if catuaba is safe or what the side effects might be.

Pregnancy and breast-feeding: There isn't enough reliable information to know if catuaba is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Interactions

We currently have no information for CATUABA overview.

Dosing

The appropriate dose of catuaba depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for catuaba. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

Heitzman, M. E., Neto, C. C., Winiarz, E., Vaisberg, A. J., and Hammond, G. B. Ethnobotany, phytochemistry and pharmacology of Uncaria (Rubiaceae). Phytochemistry 2005;66(1):5-29. View abstract.

Hemingway, S. R. and Phillipson, J. D. Proceedings: Alkaloids from S. American species of Uncaria (Rubiaceae). J.Pharm.Pharmacol. 1974;26 Suppl:113P. View abstract.

Hilepo, J. N., Bellucci, A. G., and Mossey, R. T. Acute renal failure caused by 'cat's claw' herbal remedy in a patient with systemic lupus erythematosus. Nephron 1997;77(3):361. View abstract.

Jurgensen, S., Dalbo, S., Angers, P., Santos, A. R., and Ribeiro-do-Valle, R. M. Involvement of 5-HT2 receptors in the antinociceptive effect of Uncaria tomentosa. Pharmacol Biochem.Behav 2005;81(3):466-477. View abstract.

Kitajima, M., Hashimoto, K., Yokoya, M., Takayama, H., Aimi, N., and Sakai, S. I. A new gluco indole alkaloid, 3, 4-dehydro-5-carboxystrictosidine, from Peruvian Una de Gato (Uncaria tomentosa). Chem.Pharm.Bull.(Tokyo) 2000;48(10):1410-1412. View abstract.

Kuramochi, T., Chu, J., and Suga, T. Gou-teng (from Uncaria rhynchophylla Miquel)-induced endothelium- dependent and -independent relaxations in the isolated rat aorta. Life Sci. 1994;54(26):2061-2069. View abstract.

Lamm, S., Sheng, Y., and Pero, R. W. Persistent response to pneumococcal vaccine in individuals supplemented with a novel water soluble extract of Uncaria tomentosa, C-Med-100. Phytomedicine 2001;8(4):267-274. View abstract.

Leon FR, Ortiz N, Antunez de Mayolo A, and et al. Antimutagenic activity of a freeze-dried aquous extract of Unceria tomentosa in smokers and non-smokers. 3rd European Colloquium on Ethnopharmacology / 1st International conference of Anthropology and History and Disease.Societe Europeenne d'Ethnopharmacologie Strasbourg (France)/ Dipartimento di Scienze Antropologiche Universita di Genova (Italia) 1996;255.

Lu, J. H., Tan, J. Q., Durairajan, S. S., Liu, L. F., Zhang, Z. H., Ma, L., Shen, H. M., Chan, H. Y., and Li, M. Isorhynchophylline, a natural alkaloid, promotes the degradation of alpha-synuclein in neuronal cells via inducing autophagy. Autophagy. 2012;8(1):98-108. View abstract.

Masumiya, H., Saitoh, T., Tanaka, Y., Horie, S., Aimi, N., Takayama, H., Tanaka, H., and Shigenobu, K. Effects of hirsutine and dihydrocorynantheine on the action potentials of sino-atrial node, atrium and ventricle. Life Sci 1999;65(22):2333-2341. View abstract.

Mehta, K., Gala, J., Bhasale, S., Naik, S., Modak, M., Thakur, H., Deo, N., and Miller, M. J. Comparison of glucosamine sulfate and a polyherbal supplement for the relief of osteoarthritis of the knee: a randomized controlled trial [ISRCTN25438351]. BMC.Complement Altern Med 2007;7:34. View abstract.

Menghini, L., Leporini, L., Scanu, N., Pintore, G., Ferrante, C., Recinella, L., Orlando, G., Vacca, M., and Brunetti, L. A multiherbal formulation influencing immune response in vitro. Minerva Med. 2012;103(1):13-21. View abstract.

Miller, M. J., Angeles, F. M., Reuter, B. K., Bobrowski, P., and Sandoval, M. Dietary antioxidants protect gut epithelial cells from oxidant-induced apoptosis. BMC.Complement Altern Med 2001;1:11. View abstract.

Miller, M. J., Mehta, K., Kunte, S., Raut, V., Gala, J., Dhumale, R., Shukla, A., Tupalli, H., Parikh, H., Bobrowski, P., and Chaudhary, J. Early relief of osteoarthritis symptoms with a natural mineral supplement and a herbomineral combination: a randomized controlled trial [ISRCTN38432711]. J Inflamm.(Lond) 10-21-2005;2:11. View abstract.

Mimaki, Y., Toshimizu, N., Yamada, K., and Sashida, Y. [Anti-convulsion effects of choto-san and chotoko (Uncariae Uncis cam Ramlus) in mice, and identification of the active principles]. Yakugaku Zasshi 1997;117(12):1011-1021. View abstract.

Muhammad, I., Khan, I. A., Fischer, N. H., and Fronczek, F. R. Two stereoisomeric pentacyclic oxindole alkaloids from Uncaria tomentosa: uncarine C and uncarine E. Acta Crystallogr.C. 2001;57(Pt 4):480-482. View abstract.

Ozaki, Y. [Pharmacological studies of indole alkaloids obtained from domestic plants, Uncaria rhynchophylla Miq. and Amsonia elliptica Roem. et Schult]. Nippon Yakurigaku Zasshi 1989;94(1):17-26. View abstract.

Beltrame, F. L., Filho, E. R., Barros, F. A., Cortez, D. A., and Cass, Q. B. A validated higher-performance liquid chromatography method for quantification of cinchonain Ib in bark and phytopharmaceuticals of Trichilia catigua used as Catuaba. J Chromatogr.A 6-30-2006;1119(1-2):257-263. View abstract.

Campos, M. M., Fernandes, E. S., Ferreira, J., Santos, A. R., and Calixto, J. B. Antidepressant-like effects of Trichilia catigua (Catuaba) extract: evidence for dopaminergic-mediated mechanisms. Psychopharmacology (Berl) 2005;182(1):45-53. View abstract.

Daolio, C., Beltrame, F. L., Ferreira, A. G., Cass, Q. B., Cortez, D. A., and Ferreira, M. M. Classification of commercial Catuaba samples by NMR, HPLC and chemometrics. Phytochem.Anal. 2008;19(3):218-228. View abstract.

Kletter, C., Glasl, S., Presser, A., Werner, I., Reznicek, G., Narantuya, S., Cellek, S., Haslinger, E., and Jurenitsch, J. Morphological, chemical and functional analysis of catuaba preparations. Planta Med. 2004;70(10):993-1000. View abstract.

Pizzolatti, M. G., Venson, A. F., Smania, A., Jr., Smania, Ede F., and Braz-Filho, R. Two epimeric flavalignans from Trichilia catigua (Meliaceae) with antimicrobial activity. Z.Naturforsch.C. 2002;57(5-6):483-488. View abstract.

Pizzolatti, M. G., Verdi, L. G., Brighente, I. M., Madureira, L. A., and Braz, Filho R. Minor gamma-lactones from Trichilia catigua (Meliaceae) and its precursors by GC-MS. Nat.Prod.Res. 2004;18(5):433-438. View abstract.

Queiroz, E. F., Zanolari, B., Marston, A., Guilet, D., Burgener, L., Paulo, Mde Q., and Hostettmann, K. Two new tropane alkaloids from the bark of Erythroxylum vacciniifolium Mart. (Erythroxylaceae). Nat.Prod.Commun. 2009;4(10):1337-1340. View abstract.

Tabanca, N., Pawar, R. S., Ferreira, D., Marais, J. P., Khan, S. I., Joshi, V., Wedge, D. E., and Khan, I. A. Flavan-3-ol-phenylpropanoid conjugates from Anemopaegma arvense and their antioxidant activities. Planta Med. 2007;73(10):1107-1111. View abstract.

Tang, W., Hioki, H., Harada, K., Kubo, M., and Fukuyama, Y. Antioxidant phenylpropanoid-substituted epicatechins from Trichilia catigua. J Nat.Prod. 2007;70(12):2010-2013. View abstract.

Uchino, T., Kawahara, N., Sekita, S., Satake, M., Saito, Y., Tokunaga, H., and Ando, M. Potent protecting effects of Catuaba (Anemopaegma mirandum) extracts against hydroperoxide-induced cytotoxicity. Toxicol.In Vitro 2004;18(3):255-263. View abstract.

Zanolari, B., Guilet, D., Marston, A., Queiroz, E. F., Paulo, Mde Q., and Hostettmann, K. Methylpyrrole tropane alkaloids from the bark of Erythroxylum vacciniifolium. J Nat.Prod. 2005;68(8):1153-1158. View abstract.

Zanolari, B., Guilet, D., Marston, A., Queiroz, E. F., Paulo, Mde Q., and Hostettmann, K. Tropane alkaloids from the bark of Erythroxylum vacciniifolium. J Nat.Prod. 2003;66(4):497-502. View abstract.

Zanolari, B., Wolfender, J. L., Guilet, D., Marston, A., Queiroz, E. F., Paulo, M. Q., and Hostettmann, K. On-line identification of tropane alkaloids from Erythroxylum vacciniifolium by liquid chromatography-UV detection-multiple mass spectrometry and liquid chromatography-nuclear magnetic resonance spectrometry. J Chromatogr.A 12-5-2003;1020(1):75-89. View abstract.

Agri Res Svc: Dr. Duke's phytochemical and ethnobotanical databases. www.ars-grin.gov/duke (Accessed 3 November 1999).

Lagos JB, Miguel OG, Duarte MR. Anatomical characters of catuaba (Trichilia catugua A. Juss, Meliaceae). Lat Am J Pharm 2007; 26:185-90.

Manabe H, et al. Effects of Catuaba extracts on microbial and HIV infection. In Vivo 1992;6:161-5. View abstract.

Martins NO, de Brito IM, Araújo SSO, Negri G, Carlini EA, Mendes FR. Antioxidant, anticholinesterase and antifatigue effects of Trichilia catigua (catuaba). BMC Complement Altern Med. 2018;18(1):172. View abstract.

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

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