Manaca (Brunfelsia uniflora) is a plant that is native to Brazil and other South American countries. The root has been used traditionally as medicine.
People sometimes use manaca for osteoarthritis and fluid retention, but there is no good scientific evidence to support these or any other uses.
Uses & Effectiveness
We currently have no information for MANACA overview.
Side Effects
When taken by mouth: There isn't enough reliable information to know if manaca is safe or what the side effects might be.
Special Precautions and Warnings
When taken by mouth: There isn't enough reliable information to know if manaca is safe or what the side effects might be.
Pregnancy and breast-feeding: There isn't enough reliable information to know if manaca is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.
Interactions
We currently have no information for MANACA overview.
Dosing
There isn't enough reliable information to know what an appropriate dose of manaca might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.
Jorge LF, Meniqueti AB, Silva RF, et al. Antioxidant activity and chemical composition of oleoresin from leaves and flowers of Brunfelsia uniflora. Genet Mol Res 2017;16(3). View abstract.
Weimer P, Spies LM, Haubert R, et al. Anti-inflammatory activity of Brunfelsia uniflora root extract: phytochemical characterization and pharmacologic potential of this under-investigated species. Nat Prod Res 2021;35(24):6122-6128. View abstract.
CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.