TURKEY TAIL MUSHROOM - Uses, Side Effects, and More

Ando, T., Mastuda, Y., Matsunaga, K., Fujii, T., Yoshikumi, C., and Nomoto, K. [Effect of PSK on the recovery of macrophage function in tumor-bearing mice]. Gan To Kagaku Ryoho 1984;11(4):827-834. View abstract.

Chung, C. H., Go, P., and Chang, K. H. PSK immunotherapy in cancer patients--a preliminary report. Zhonghua Min Guo.Wei Sheng Wu Ji.Mian.Yi.Xue.Za Zhi. 1987;20(3):210-216. View abstract.

Ebina, T. and Murata, K. [Antitumor effect of intratumoral administration of BRM: inhibition of tumor cell invasion in vitro]. Gan To Kagaku Ryoho 1995;22(11):1626-1628. View abstract.

Ebina, T. and Murata, K. Antitumor effect of PSK at a distant site: tumor-specific immunity and combination with other chemotherapeutic agents. Jpn.J Cancer Res 1992;83(7):775-782. View abstract.

Fujiwara, S., Suzumori, K., Yasui, Y., Yamamoto, T., and Yagami, Y. [The effect of immunochemotherapy with PSK in malignant tumors of the female reproductive organs]. Gan No Rinsho 1986;32(1):65-70. View abstract.

Fukuo, Y., Terashi, A., Hayashi, Y., Yano, Y., and Atarashi, J. [A clinical trial of cis-platinum (II) in combination with PSK and FT-207 in advanced stomach cancer]. Gan To Kagaku Ryoho 1985;12(4):960-965. View abstract.

Hattori, T., Nakajima, T., Nakazato, H., Tanabe, T., Kikuchi, K., Abe, O., Kondo, T., Taguchi, T., Komi, N., Sugimachi, K., and . Postoperative adjuvant immunochemotherapy with mitomycin C, tegafur, PSK and/or OK-432 for gastric cancer, with special reference to the change in stimulation index after gastrectomy. Jpn.J Surg 1990;20(2):127-136. View abstract.

Hirono, M., Yoshinaka, K., Matsuki, K., Noso, Y., Oride, M., Toge, T., Niimoto, M., and Hattori, T. [Surgical treatment of Borrmann type 4 (diffuse) gastric cancer]. Gan No Rinsho 1984;30(6 Suppl):717-723. View abstract.

Ichihashi, H., Kondo, T., and Nakazato, H. [Clinical results of a randomized controlled trial on the effect of adjuvant immunochemotherapy using Esquinon and Krestin in patients with curatively resected gastric cancer--7-year survival--Cooperative Study Group for Cancer Immunochemotherapy, Tokai Gastrointestinal Oncology Group]. Gan To Kagaku Ryoho 1987;14(9):2758-2766. View abstract.

Ikeda, T., Sakai, T., Suito, T., and Kosaki, G. [Evaluation of postoperative immunochemotherapy in lung cancer]. Gan To Kagaku Ryoho 1986;13(4 Pt 1):1044-1049. View abstract.

Ikuzawa, M., Matsunaga, K., Nishiyama, S., Nakajima, S., Kobayashi, Y., Andoh, T., Kobayashi, A., Ohhara, M., Ohmura, Y., Wada, T., and . Fate and distribution of an antitumor protein-bound polysaccharide PSK (Krestin). Int J Immunopharmacol 1988;10(4):415-423. View abstract.

Sakamoto, J., Koike, A., Saji, S., Teramukai, S., Ohashi, Y., and Nakazato, H. Preoperative serum immunosuppressive acidic protein (IAP) test for the prognosis of gastric cancer: a statistical study of the threshold level and evaluation of the effect of the biological response modifier PSK. Surg Today 1992;22(6):530-536. View abstract.

Collins RA, Ng TB. Polysaccharopeptide from Coriolus versicolor has potential for use against human immunodeficiency virus type 1 infection. Life Sci 1997;60:PL383-7. View abstract.

Cortés Bordoy J, de Santiago García J, Agenjo González M, et al. Effect of a multi-ingredient Coriolus-versicolor-based vaginal gel in women with HPV-dependent cervical lesions: The papilobs real-life prospective study. Cancers (Basel) 2023;15(15):3863. View abstract.

Criscuolo AA, Sesti F, Piccione E, et al. Therapeutic efficacy of a Coriolus versicolor-based vaginal gel in women with cervical uterine high-risk HPV infection: A retrospective observational study. Adv Ther 2021;38(2):1202-1211. View abstract.

Dong Y, Kwan CY, Chen ZN, et al. Antitumor effects of a refined polysaccharide peptide fraction isolated from Coriolus versicolor: in vitro and in vivo studies. Res Commun Mol Pathol Pharmacol 1996;92:140-8. View abstract.

Dong Y, Yang MM, Kwan CY. In vitro inhibition of proliferation of HL-60 cells by tetrandrine and coriolus versicolor peptide derived from Chinese medicinal herbs. Life Sci 1997;60:PL135-40. View abstract.

Eliza WL, Fai CK, Chung LP. Efficacy of Yun Zhi (Coriolus versicolor) on survival in cancer patients: systematic review and meta-analysis. Recent Pat Inflamm Allergy Drug Discov 2012;6(1):78-87. View abstract.

Fukushima M. Adjuvant therapy of gastric cancer: the Japanese experience. Semin Oncol 1996;23:369-78. View abstract.

Gil-Antuñano SP, Serrano Cogollor L, López Díaz AC, et al. Efficacy of a coriolusversicolor-based vaginal gel in human papillomavirus-positive women older than 40 years: A sub-analysis of PALOMA study. J Pers Med 2022;12(10):1559. View abstract.

Go P, Chung CH. Adjuvant PSK immunotherapy in patients with carcinoma of the nasopharynx. J Int Med Res 1989;17:141-9. View abstract.

Gong S, Zhang HQ, Yin WP, et al. Involvement of interleukin-2 in analgesia produced by Coriolus versicolor polysaccharide peptides. Chung Kuo Yao Li Hsueh Pao 1998;19:67-70. View abstract.

Harada M, Matsunaga K, Oguchi Y, et al. Oral administration of PSK can improve the impaired anti-tumor CD4+ T-cell response in gut associated lymphoid tissue (GALT) of specific-pathogen-free mice. Int J Cancer 1997;70:362-72. View abstract.

Hayakawa K, Mitsuhashi N, Saito Y, et al. Effect of Krestin as adjuvant treatment following radical radiotherapy in non-small cell lung cancer patients. Cancer Detect Prev 1997;21:71-7. View abstract.

Hor SY, Ahmad M, Farsi E, Lim CP, Asmawi MZ, Yam MF. Acute and subchronic oral toxicity of Coriolus versicolor standardized water extract in Sprague-Dawley rats. J Ethnopharmacol 2011;137(3):1067-76. View abstract.

Iino Y, Yokoe T, Maemura M, et al. Immunochemotherapies versus chemotherapy as adjuvant treatment after curative resection of operable breast cancer. Anticancer Res 1995;15:2907-11. View abstract.

Jin M, Zhou W, Jin C, et al. Anti-inflammatory activities of the chemical constituents isolated from Trametes versicolor. Nat Prod Res 2019;33(16):2422-5. View abstract.

Kanoh T, Saito K, Matsunaga K, et al. Enhancement of the antitumor effect by the concurrent use of a monoclonal antibody and the protein bound polysaccharide PSK in mice bearing a human cancer cell line. In Vivo 1994;8:241-5. View abstract.

Kim HS, Kacew S, Lee BM. In vitro chemopreventive effects of plant polysaccharides (Aloe barbadensis miller, Lentinus edodes, Ganoderma lucidum and Coriolus versicolor). Carcinogenesis 1999;20:1637-40. View abstract.

Kobayashi H, Matsunaga K, Oguchi Y. Antimetastatic effects of PSK (Krestin), a protein-bound polysaccharide obtained from basidiomycetes: an overview. Cancer Epidemiol Biomarkers Prev 1995;4:275-81. View abstract.

Kondo T, Sakamoto J, Nakazato H. Alternating immunochemotherapy of advanced gastric carcinoma: a randomized comparison of carbazilquinone and PSK to carbazilquinone in patients with curative gastric resection. Biotherapy 1991;3:287-95. View abstract.

Maehara Y, Inutsuka S, Takeuchi H, et al. Postoperative PSK and OK-432 immunochemotherapy for patients with gastric cancer. Cancer Chemother Pharmacol 1993;33:171-5. View abstract.

Meng F, Lin Y, Hu L, Feng W, Su P, Wu L. The therapeutic effect of Coriolus versicolor fruiting body on STZ-induced ICR diabetic mice. J Healthc Eng 2022;2022:7282453. View abstract.

Mitomi T, Tsuchiya S, Iijima N, et al. Randomized, controlled study on adjuvant immunochemotherapy with PSK in curatively resected colorectal cancer. The Cooperative Study Group of Surgical Adjuvant Immunochemotherapy for Cancer of Colon and Rectum (Kanagawa). Dis Colon Rectum 1992;35:123-30. View abstract.

Mizutani Y, Yoshida O. Activation by the protein-bound polysaccharide PSK (krestin) of cytotoxic lymphocytes that act on fresh autologous tumor cells and T24 human urinary bladder transitional carcinoma cell line in patients with urinary bladder cancer. J Urol 1991;145:1082-7. View abstract.

Morimoto T, Ogawa M, Orita K, et al. Postoperative adjuvant randomised trial comparing chemoendocrine therapy, chemotherapy and immunotherapy for patients with stage II breast cancer: 5-year results from the Nishinihon Cooperative Study Group of Adjuvant Chemoendocrine Therapy for Breast Cancer (ACETBC) of Japan. Eur J Cancer 1996;32A:235-42. View abstract.

Nakazato H, Koike A, Saji S, et al. Efficacy of immunochemotherapy as adjuvant treatment after curative resection of gastric cancer. Study Group of Immunochemotherapy with PSK for Gastric Cancer. Lancet 1994;343:1122-6. View abstract.

Ng TB, Chan WY. Polysaccharopeptide from the mushroom Coriolus versicolor possesses analgesic activity but does not produce adverse effects on female reproductive or embryonic development in mice. Gen Pharmacol 1997;29:269-73. View abstract.

Ng TB. A review of research on the protein-bound polysaccharide (polysaccharopeptide, PSP) from the mushroom Coriolus versicolor (Basidiomycetes: Polyporaceae). Gen Pharmacol 1998;30:1-4. View abstract.

Nikolic M, Lazarevic N, Novakovic J, et al. Characterization, in vitro biological activity and in vivo cardioprotective properties of Trametes versicolor (L.:Fr.) quél. heteropolysaccharides in a rat model of metabolic syndrome. Pharmaceuticals (Basel) 2023;16(6):787. View abstract.

Nio Y, Tsubono M, Tseng CC, et al. Immunomodulation by orally administered protein-bound polysaccharide PSK in patients with gastrointestinal cancer. Biotherapy 1992;4:117-28. View abstract.

Ogoshi K, Satou H, Isono K, et al. Immunotherapy for esophageal cancer. A randomized trial in combination with radiotherapy and radiochemotherapy. Cooperative Study Group for Esophageal Cancer in Japan. Am J Clin Oncol 1995;18:216-22. View abstract.

Palacios S, Losa F, Dexeus D, Cortés J. Beneficial effects of a Coriolus versicolor-based vaginal gel on cervical epithelization, vaginal microbiota and vaginal health: a pilot study in asymptomatic women. BMC Womens Health 2017;17(1):21. View abstract.

Qian ZM, Xu MF, Tang PL. Polysaccharide peptide (PSP) restores immunosuppression induced by cyclophosphamide in rats. Am J Chin Med 1997;25:27-35.. View abstract.

Razmovski-Naumovski V, Kimble B, Laurenti D, Nammi S, Norimoto H, Chan K. Polysaccharide peptide extract from Coriolus versicolor increased T(max) of tamoxifen and maintained biochemical serum parameters, with no change in the metabolism of tamoxifen in the rat. Front Pharmacol 2022;13:857864. View abstract.

Serrano L, López AC, González SP, et al. Efficacy of a Coriolus versicolor-based vaginal gel in women with human papillomavirus-dependent cervical lesions: The PALOMA study. J Low Genit Tract Dis 2021;25(2):130-136. View abstract.

Sugimachi K, Maehara Y, Ogawa M, et al. Dose intensity of uracil and tegafur in postoperative chemotherapy for patients with poorly differentiated gastric cancer. Cancer Chemother Pharmacol 1997;40:233-8. View abstract.

Suto T, Fukuda S, Moriya N, et al. Clinical study of biological response modifiers as maintenance therapy for hepatocellular carcinoma. Cancer Chemother Pharmacol 1994;33 Suppl:S145-8. View abstract.

Tochikura TS, Nakashima H, Hirose K, et al. A biological response modifier, PSK, inhibits human immunodeficiency virus infection in vitro. Biochem Biophys Res Commun 1987;148:726-33. View abstract.

Toi M, Hattori T, Akagi M, et al. Randomized adjuvant trial to evaluate the addition of tamoxifen and PSK to chemotherapy in patients with primary breast cancer. 5-Year results from the Nishi-Nippon Group of the Adjuvant Chemoendocrine Therapy for Breast Cancer Organization. Cancer 1992;70:2475-83. View abstract.

Torisu M, Hayashi Y, Ishimitsu T, et al. Significant prolongation of disease-free period gained by oral polysaccharide K (PSK) administration after curative surgical operation of colorectal cancer. Cancer Immunol Immunother 1990;31:261-8. View abstract.

Tsukagoshi S, Hashimoto Y, Fujii G, et al. Krestin (PSK). Cancer Treat Rev 1984;11:131-55. View abstract.

Wang HX, Ng TB, Liu WK, et al. Polysaccharide-peptide complexes from the cultured mycelia of the mushroom Coriolus versicolor and their culture medium activate mouse lymphocytes and macrophages. Int J Biochem Cell Biol 1996;28:601-7. View abstract.

Wasser SP, Weis AL. Therapeutic effects of substances occurring in higher Basidiomycetes mushrooms: a modern perspective. Crit Rev Immunol 1999;19:65-96. View abstract.

Yeung JH and Or PM. Polysaccharide peptides from Coriolus versicolor competitively inhibit tolbutamide 4-hydroxylation in specific human CYP2C9 isoform and pooled human liver microsomes. Phytomedicine 2011;18(13):1170-5. View abstract.

Yeung JH, Chiu LC, Ooi VE. Effect of polysaccharide peptide (PSP) on glutathione and protection against paracetamol-induced hepatotoxicity in the rat. Methods Find Exp Clin Pharmacol 1994;16:723-9. View abstract.

Yokoe T, Iino Y, Takei H, et al. HLA antigen as predictive index for the outcome of breast cancer patients with adjuvant immunochemotherapy with PSK. Anticancer Res 1997;17:2815-8. View abstract.

Zhong L, Yan P, Lam WC, et al. Coriolus versicolor and Ganoderma lucidum related natural products as an adjunct therapy for cancers: a systematic review and meta-analysis of randomized controlled trials. Front Pharmacol 2019;10:703. View abstract.