YOGURT: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

Yogurt is a dairy product made by fermenting milk using one or more bacteria, such as L. delbrueckii subsp. bulgaricus and S. thermophilus.

Yogurt contains bacteria which may help restore the normal bacteria in the digestive tract and vagina. This might help treat diarrhea and vaginal infections.

People use yogurt for constipation, high cholesterol, lactose intolerance, diarrhea, and many other conditions, but there is no good scientific evidence to support many of these uses.

Don't confuse yogurt with probiotics, fermented milk, or kefir. These are not the same.

Uses & Effectiveness

Possibly Effective for

Constipation. Eating a specific yogurt containing probiotics (Activia) seems to help increase bowel movements in people with constipation.
High levels of cholesterol or other fats (lipids) in the blood (hyperlipidemia). Eating certain types of yogurt containing probiotics seems to somewhat lower cholesterol levels in people with high cholesterol.
Inability to properly digest the sugar lactose (lactose intolerance). Eating yogurt with live bacterial cultures seems to improve lactose tolerance in children and adults who are unable to fully digest lactose.

There is interest in using yogurt for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.

Side Effects

When taken by mouth: Yogurt is commonly consumed in foods. It's usually well-tolerated.

When used in the vagina: Yogurt is possibly safe when used appropriately.

Special Precautions and Warnings

When taken by mouth: Yogurt is commonly consumed in foods. It's usually well-tolerated.

When used in the vagina: Yogurt is possibly safe when used appropriately.

Pregnancy: Yogurt is commonly consumed in foods. Is it possibly safe when used in the vagina while pregnant.

Breast-feeding: Yogurt is commonly consumed in foods. There isn't enough reliable information to know if yogurt is safe to use in the vagina when breast-feeding. Stay on the safe side and avoid use.

Weakened immune system: Although rare, live bacteria in yogurt can might cause illness in people with weakened immune systems. If you have a weakened immune system, talk to your healthcare provider before eating large amounts of yogurt that contain live bacteria for prolonged periods of time.

Milk allergy: Many people allergic to milk are also allergic to yogurt. If you are allergic to milk, talk with your healthcare provider before trying yogurt.

Interactions

Moderate Interaction

Be cautious with this combination

Antibiotics (Tetracycline antibiotics) interacts with YOGURT
Yogurt might decrease how much tetracycline antibiotic the body absorbs, which might decrease the effects of tetracycline antibiotics. To avoid this interaction, take yogurt two hours before or four hours after taking tetracyclines.
Ciprofloxacin (Cipro) interacts with YOGURT
Ciprofloxacin is an antibiotic. Yogurt might decrease how much ciprofloxacin the body absorbs, which might decrease the effects of ciprofloxacin. To avoid this interaction, take yogurt at least one hour after ciprofloxacin.

Minor Interaction

Be watchful with this combination

NILOTINIB (Tasigna) interacts with YOGURT
Yogurt might increase the absorption of nilotinib by a small amount. But it does not seem to increase side effects from nilotinib.

Dosing

Yogurt is commonly eaten in foods. In the US, most yogurt is made using the probiotics Lactobacillus delbrueckii subsp. bulgaricus and Streptococcus thermophilus. Some yogurts also contain Lactobacillus acidophilus, Lacticaseibacillus rhamnosus, Enterococcus faecium, and Bidifobacterium animalis.

As medicine, yogurt has most often been consumed by adults as 250 mL or 250 grams by mouth daily for 1-16 weeks. Speak with a healthcare provider to find out what type of product and dose might be best for a specific condition.

View References

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Rosado JL, Solomons NW, Allen LH. Lactose digestion from unmodified, low-fat and lactose-hydrolyzed yogurt in adult lactose-maldigesters. Eur J Clin Nutr 1992;46:61-7.. View abstract.

Rosenberg L, Robles YP, Li S, Ruiz-Narvaez EA, Palmer JR. A prospective study of yogurt and other dairy consumption in relation to incidence of type 2 diabetes among black women in the USA. Am J Clin Nutr. 2020;112(3):512-518. View abstract.

Santiago S, Sayón-Orea C, Babio N, et al. Yogurt consumption and abdominal obesity reversion in the PREDIMED study. Nutr Metab Cardiovasc Dis. 2016 Jun;26(6):468-75. View abstract.

Schaafsma G, Meuling WJ, van Dokkum W, Bouley C. Effects of a milk product, fermented by Lactobacillus acidophilus and with fructo-oligosaccharides added, on blood lipids in male volunteers. Eur J Clin Nutr 1998;52:436-40. View abstract.

Schmid D, Song M, Zhang X, et al. Yogurt consumption in relation to mortality from cardiovascular disease, cancer, and all causes: a prospective investigation in 2 cohorts of US women and men. Am J Clin Nutr. 2020;111(3):689-697. View abstract.

Shaalan O, Gad HMA, Riad MI. Comparison of antibacterial effect of probiotic yogurt and xylitol-containing chewing gum in geriatric patients: A randomized controlled clinical trial. Acta Stomatol Croat 2021;55(4):380-389. View abstract.

Shafie M, Homayouni Rad A, Mirghafourvand M. Effects of prebiotic-rich yogurt on menopausal symptoms and metabolic indices in menopausal women: a triple-blind randomised controlled trial. Int J Food Sci Nutr 2022. View abstract.

Shalev E, Battino S, Weiner E, et al. Ingestion of yogurt containing Lactobacillus acidophilus compared with pasteurized yogurt as prophylaxis for recurrent candidal vaginitis and bacterial vaginosis. Arch Fam Med 1996;5:593-6. View abstract.

Sheu BS, Wu JJ, Lo CY, et al. Impact of supplement with Lactobacillus- and Bifidobacterium-containing yogurt on triple therapy for Helicobacter pylori eradication. Aliment Pharmacol Ther 2002;16:1669-75.. View abstract.

Siitonen S, Vapaatalo H, Salminen S, et al. Effect of Lactobacillus GG yogurt in prevention of antibiotic associated diarrhea. Ann Med 1990;22:57-9. View abstract.

Sun J, Song J, Yang J, et al. Higher yogurt consumption is associated with lower risk of colorectal cancer: A systematic review and meta-analysis of observational studies. Front Nutr 2022;8:789006. View abstract.

Suzuki T, Masui A, Nakamura J, et al. Yogurt Containing Lactobacillus gasseri Mitigates Aspirin-Induced Small Bowel Injuries: A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial. Digestion. 2017;95(1):49-54. View abstract.

Touhami M, Boudraa G, Mary JY, et al. Clinical consequences of replacing milk with yogurt in persistent infantile diarrhea. Ann Pediatr (Paris) 1992;39:79-86. View abstract.

Uchida K, Shimamura R, Ikefuchi R, et al. Effects of yogurt intake on cardiovascular strain during outdoor interval walking training by older people in midsummer: a randomized controlled study. Int J Environ Res Public Health 2022;19(8):4715. View abstract.

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Wheeler JG, Shema SJ, Bogle ML, et al. Immune and clinical impact of Lactobacillus acidophilus on asthma. Ann Allergy Asthma Immunol 1997;79:229-33. View abstract.

White KM, Bauer SJ, Hartz KK, Baldridge M. Changes in body composition with yogurt consumption during resistance training in women. Int J Sport Nutr Exerc Metab. 2009 Feb;19(1):18-33. View abstract.

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Yang JJ, Yu D, Xiang YB, et al. Association of dietary fiber and yogurt consumption with lung cancer risk: A pooled analysis. JAMA Oncol. 2020;6(2):e194107. View abstract.

Yanni AE, Konstantopoulos P, Kartsioti K, et al. Effects of 12-week, non-energy-restricted dietary intervention with conventional yogurt ?n appetite hormone responses of type 2 diabetic patients. Food Sci Nutr 2021;9(12):6610-6616. View abstract.

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Yoon H, Kim N, Kim JY, Park SY, Park JH, Jung HC, Song IS. Effects of multistrain probiotic-containing yogurt on second-line triple therapy for Helicobacter pylori infection. J Gastroenterol Hepatol. 2011 Jan;26(1):44-8. View abstract.

Yuzbashian E, Asghari G, Mirmiran P, Chan CB, Azizi F. Changes in dairy product consumption and subsequent type 2 diabetes among individuals with prediabetes: Tehran Lipid and Glucose Study. Nutr J 2021;20(1):88. View abstract.

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