Crippa A, Tesei A, Sangiorgio F, et al. Behavioral and cognitive effects of docosahexaenoic acid in drug-naïve children with attention-deficit/hyperactivity disorder: a randomized, placebo-controlled clinical trial. Eur Child Adolesc Psychiatry 2019;28(4):571-83. View abstract.
Danthiir V, Hosking DE, Nettelbeck T, et al. An 18-mo randomized, double-blind, placebo-controlled trial of DHA-rich fish oil to prevent age-related cognitive decline in cognitively normal older adults. Am J Clin Nutr. 2018;107(5):754-762. View abstract.
Davidson MH, Maki KC, Kalkowski J, et al. Effects of docosahexaenoic acid on serum lipoproteins in patients with combined hyperlipidemia: a randomized, double-blind, placebo-controlled trial. J.Am.Coll.Nutr. 1997;16(3):236-243. View abstract.
Decsi T, Koletzko B. N-3 fatty acids and pregnancy outcomes. Curr Opin Clin Nutr Metab Care 2005;8:161-6. View abstract.
Decsi, T., Campoy, C., and Koletzko, B. Effect of N-3 polyunsaturated fatty acid supplementation in pregnancy: the Nuheal trial. Adv.Exp Med Biol 2005;569:109-113. View abstract.
Demmelmair H, MacDonald A, Kotzaeridou U, et al. Determinants of plasma docosahexaenoic acid levels and their relationship to neurological and cognitive functions in PKU patients: A double blind randomized supplementation study. Nutrients. 2018;10(12). pii: E1944. View abstract.
Dijck-Brouwer DA, Hadders-Algra M, Bouwstra H, et al. Lower fetal status of docosahexaenoic acid, arachidonic acid and essential fatty acids is associated with less favorable neonatal neurological condition. Prostaglandins Leukot Essent Fatty Acids 2005;72:21-8. View abstract.
Drover JR, Felius J, Hoffman DR, Castañeda YS, Garfield S, Wheaton DH, Birch EE. A randomized trial of DHA intake during infancy: school readiness and receptive vocabulary at 2-3.5 years of age. Early Hum Dev. 2012 Nov;88(11):885-91. View abstract.
Drugs in Pregnancy and Lactation 2012;25(4);3-4
Emsley R, Chiliza B, Asmal L, du Plessis S, Phahladira L, van Niekerk E, van Rensburg SJ, Harvey BH. A randomized, controlled trial of omega-3 fatty acids plus an antioxidant for relapse prevention after antipsychotic discontinuation in first-episode schizophrenia. Schizophr Res. 2014 Sep;158(1-3):230-5. View abstract.
Erkkila AT, Lehto S, Pyorala K, Uusitupa MI. n-3 Fatty acids and 5-y risks of death and cardiovascular disease events in patients with coronary artery disease. Am J Clin Nutr 2003;78:65-71.. View abstract.
Escamilla-Nuñez MC, Barraza-Villarreal A, Hernández-Cadena L, Navarro-Olivos E, Sly PD, Romieu I. Omega-3 fatty acid supplementation during pregnancy and respiratory symptoms in children. Chest. 2014 Aug;146(2):373-82. View abstract.
FDA announces qualified health claims for omega-3 fatty acids. Available at: https://www.fda.gov/Food/LabelingNutrition/ucm072756.htm. Accessed April 15 2019.
FDA. Center for Food Safety and Applied Nutrition. Letter regarding dietary supplement health claim for omega-3 fatty acids and coronary heart disease. Available at: https://www.fda.gov/ohrms/dockets/dockets/95s0316/95s-0316-Rpt0272-38-Appendix-D-Reference-F-FDA-vol205.pdf. (Accessed February 7, 2017).
Fougère H, Bilodeau JF, Lavoie PM, et al. Docosahexaenoic acid-rich algae oil supplementation on breast milk fatty acid profile of mothers who delivered prematurely: a randomized clinical trial. Sci Rep 2021;11(1):21492. View abstract.
Fradet V, Cheng I, Casey G, et al. Dietary omega-3 fatty acids, cyclooxygenase-2 genetic variation, and aggressive prostate cancer risk. Clin Cancer Res. 2009 Apr 1;15(7):2559-66. View abstract.
Fu YQ, Zheng JS, Yang B, Li D. Effect of individual omega-3 fatty acids on the risk of prostate cancer: a systematic review and dose-response meta-analysis of prospective cohort studies. J Epidemiol. 2015;25(4):261-74. View abstract.
Gamoh S, Hashimoto M, Sugioka K, et al. Chronic administration of docosahexaenoic acid improves reference memory-related learning ability in young rats. Neuroscience 1999;93:237-41. View abstract.
García-Layana A, Recalde S, Alamán AS, Robredo PF. Effects of lutein and docosahexaenoic Acid supplementation on macular pigment optical density in a randomized controlled trial. Nutrients. 2013 Feb 15;5(2):543-51. View abstract.
Garmendia ML, Casanello P, Flores M, Kusanovic JP, Uauy R. The effects of a combined intervention (docosahexaenoic acid supplementation and home-based dietary counseling) on metabolic control in obese and overweight pregnant women: the MIGHT study. Am J Obstet Gynecol 2021;224(5):526. e1-526.e25. View abstract.
Gibson RA. Long-chain polyunsaturated fatty acids and infant development (editorial). Lancet 1999;354:1919.
Giriraja KV, Bhatnagar SK, Tomlinson L, Sancilio F. An open-label, multicenter, phase 2 study of a food enriched with docosahexaenoic acid in adults with sickle cell disease. Prostaglandins Leukot Essent Fatty Acids 2023;193:102574. View abstract.
González-Ravina C, Aguirre-Lipperheide M, Pinto F, et al. Effect of dietary supplementation with a highly pure and concentrated docosahexaenoic acid (DHA) supplement on human sperm function. Reprod Biol. 2018;18(3):282-288. View abstract.
Gould JF, Makrides M, Colombo J, Smithers LG. Randomized controlled trial of maternal omega-3 long-chain PUFA supplementation during pregnancy and early childhood development of attention, working memory, and inhibitory control. Am J Clin Nutr. 2014 Apr;99(4):851-9. View abstract.
Gould JF, Makrides M, Gibson RA, et al. Neonatal docosahexaenoic acid in preterm infants and intelligence at 5 years. N Engl J Med. 2022;387(17):1579-1588. View abstract.
Gould JF, Treyvaud K, Yelland LN, et al. Seven-Year Follow-up of Children Born to Women in a Randomized Trial of Prenatal DHA Supplementation. JAMA. 2017;317(11):1173-1175. View abstract.
Grimsgaard S, Bonaa KH, Hansen JB, Nordoy A. Highly purified eicosapentaenoic acid and docosahexaenoic acid in humans have similar triacylglycerol-lowering effects but divergent effects on serum fatty acids. Am J Clin Nutr 1997;66:649-59. View abstract.
Grosso G, Pajak A, Marventano S, Castellano S, Galvano F, Bucolo C, Drago F, Caraci F. Role of omega-3 fatty acids in the treatment of depressive disorders: a comprehensive meta-analysis of randomized clinical trials. PLoS One. 2014 May 7;9(5):e96905. View abstract.
Guillot M, Synnes A, Pronovost E, et al. Maternal high-dose DHA supplementation and neurodevelopment at 18-22 months of preterm children. Pediatrics. 2022;150(1):e2021055819. View abstract.
Guo XF, Li KL, Li JM, Li D. Effects of EPA and DHA on blood pressure and inflammatory factors: a meta-analysis of randomized controlled trials. Crit Rev Food Sci Nutr. 2019;59(20):3380-3393. View abstract.
Cicero, A. F., Derosa, G., Manca, M., Bove, M., Borghi, C., and Gaddi, A. V. Different effect of psyllium and guar dietary supplementation on blood pressure control in hypertensive overweight patients: a six-month, randomized clinical trial. Clin.Exp.Hypertens. 2007;29(6):383-394. View abstract.
Agha FP, Nostrant TT, Fiddian-Green RG. Giant colonic bezoar: a medication bezoar due to psyllium seed husks. Am J Gastroenterol 1984;79:319-21. View abstract.
Alabaster O, Tang Z, Shivapurkar N. Dietary fiber and the chemopreventive modelation of colon carcinogenesis. Mutation Res 1996;350:185-97.. View abstract.
Alabaster O, Tang ZC, Frost A, Shivapurkar N. Potential synergism between wheat bran and psyllium: enhanced inhibition of colon cancer. Cancer Lett 1993;75:53-8. View abstract.
Anderson JW, Allgood LD, Lawrence A, et al. Cholesterol-lowering effects of psyllium intake adjunctive to diet therapy in men and women with hypercholesterolemia: meta-analysis of 8 controlled trials. Am J Clin Nutr 2000;71:472-9. View abstract.
Anderson JW, Allgood LD, Turner J, et al. Effects of psyllium on glucose and serum lipid responses in men with type 2 diabetes and hypercholesterolemia. Am J Clin Nutr 1999;70:466-73. View abstract.
Anderson JW, Davidson MH, Blonde L, et al. Long-term cholesterol-lowering effects of psyllium as an adjunct to diet therapy in the treatment of hypercholesterolemia. Am J Clin Nutr 2000;71:1433-8. View abstract.
Dennison BA, Levine DM. Randomized, double-blind, placebo-controlled, two-period crossover clinical trial of psyllium fiber in children with hypercholesterolemia. J Pediatr 1993;123:24-9. View abstract.
Flannery J, Raulerson A. Hypercholesterolemia: a look at low-cost treatment and treatment adherence. J Am Acad Nurse Pract 2000;12:462-6. View abstract.
Florholmen J, Arvidsson-Lenner R, Jorde R, Burhol PG. The effect of Metamucil on postprandial blood glucose and plasma gastric inhibitory peptide in insulin-dependent diabetics (abstract). Acta Med Scand 1982;212:237-9. View abstract.
Ford AC1, Talley NJ, Spiegel BM, et al. Effect of fibre, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome: systematic review and meta-analysis. BMJ. 2008 Nov 13;337:a2313. View abstract.
Frape DL, Jones AM. Chronic and postprandial responses of plasma insulin, glucose and lipids in volunteers given dietary fibre supplements. Br J Nutr. 1995 May;73(5):733-51. View abstract.
Frati Munari AC, Benitez Pinto W, Raul Ariza Andraca C, Casarrubias M. Lowering glycemic index of food by acarbose and Plantago psyllium mucilage. Arch Med Res 1998;29:137-41. View abstract.
Freeman GL. Psyllium hypersensitivity. Ann Allergy 1994;73:490-2. View abstract.
Fujimori S, Tatsuguchi A, Gudis K, et al. High dose probiotic and prebiotic cotherapy for remission induction of active Crohn's disease. J Gastroenterol Hepatol. 2007 Aug;22(8):1199-204. View abstract.
Ganji V, Kies CV. Psyllium husk fibre supplementation to soybean and coconut oil diets of humans: effect on fat digestibility and faecal fatty acid excretion. Eur J Clin Nutr 1994;48:595-7. View abstract.
Garcia JJ, Fernandez N, Carriedo D, et al. Hydrosoluble fiber (Plantago ovata husk) and levodopa I: experimental study of the pharmacokinetic interaction. Eur Neuropsychopharmacol 2005;15(5):497-503. View abstract.
Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. View abstract.
Gelissen IC, Brodie B, Eastwood MA. Effect of Plantago ovata (psyllium) husk and seeds on sterol metabolism: studies in normal and ileostomy subjects. Am J Clin Nutr 194;59:395-400. View abstract.
Gerber M. Fiber and breast cancer: another piece of the puzzle--but still an incomplete picture. J Natl Cancer Inst 1996;88:857-8. View abstract.
Gibb RD, Sloan KJ, McRorie JW Jr. Psyllium is a natural nonfermented gel-forming fiber that is effective for weight loss: A comprehensive review and meta-analysis. J Am Assoc Nurse Pract 2023;35(8):468-476. View abstract.
Golechha AC, Chadda VS, Chadda S, et al. Role of ispaghula husk in the management of irritable bowel syndrome (a randomized double-blind crossover study). J Assoc Physicians India. 1982 Jun;30(6):353-5. View abstract.
González AP, Flores-Ramírez A, Gutiérrez-Castro KP, et al. Reduction of small dense LDL and Il-6 after intervention with Plantago psyllium in adolescents with obesity: a parallel, double blind, randomized clinical trial. Eur J Pediatr 2021;180(8):2493-2503. View abstract.
Gupta RR, Agrawal CG, Singh CP, Ghatak A. Lipid-lowering efficacy of psyllium hydrophilic mucilloid in non insulin dependent diabetes mellitus with hyperlipidaemia. Indian J Med Res 1994;100:237-41. View abstract.
Haji-Ali-Nili N, Khoshzaban F, Karimi M, et al. Effect of a natural eye drop, made of Plantago Ovata mucilage on improvement of dry eye symptoms: A randomized, double-blind clinical trial. Iran J Pharm Res. 2019;18(3):1602-1611. View abstract.
Hallert C, Kaldma M, Petersson BG. Ispaghula husk may relieve gastrointestinal symptoms in ulcerative colitis in remission. Scand J Gastroenterol 1991;26:747-50.. View abstract.
Hasheminasab FS, Hashemi SM, Dehghan A, et al. Effects of a Plantago ovata-based herbal compound in prevention and treatment of oral mucositis in patients with breast cancer receiving chemotherapy: A double-blind, randomized, controlled crossover trial. J Integr Med. 2020;18(3):214-221.View abstract.
Heather DJ, Howell L, Montana M, et al. Effect of a bulk-forming cathartic on diarrhea in tube-fed patients. Heart Lung 1991;20:409-13. View abstract.
Ho Y, Tan M, Seow-Choen F. Micronized purified flavonidic fraction compared favorably with rubber band ligation and fiber alone in the management of bleeding hemorrhoids. Dis Colon Rectum 2000;43:66-9. View abstract.
Hotz J, Plein K. [Effectiveness of plantago seed husks in comparison with wheat brain on stool frequency and manifestations of irritable colon syndrome with constipation]. Med Klin (Munich). 1994 Dec 15;89(12):645-51. View abstract.
Jalihal A, Kurian G. Ispaghula therapy in irritable bowel syndrome: improvement in overall well-being is related to reduction bowel dissatisfaction. J Gastroenterol Hepatol 1990;5:507-13. View abstract.
James JM, Cooke SK, Barnett A, Sampson HA. Anaphylactic reactions to a psyllium-containing cereal. J Allergy Clin Immunol 1991;88:402-8.. View abstract.
Jarjis HA, Blackburn NA, Redfern JS, Read NW. The effect of ispaghula (Fybogel and Metamucil) and guar gum on glucose tolerance in man. Br J Nutr 1984;51:371-8.. View abstract.
Jenkins DJ, Kendall CW, Axelsen M, et al. Viscous and nonviscous fibres, nonabsorbable and low glycaemic index carbohydrates, blood lipids and coronary heart disease. Curr Opin Lipidol 2000;11:49-56. View abstract.
Jenkins DJ, Kendall CW, Vuksan V. Viscous fibers, health claims, and strategies to reduce cardiovascular disease risk. Am J Clin Nutr 2000;71:401-2. View abstract.
Jenkins DJ, Wolever TM, Vidgen E, et al. Effect of psyllium in hypercholesterolemia at two monosaturated fatty acid intakes. Am J Clin Nutr 1997;65:1524-33. View abstract.
Jensen CD, Haskell W, Whittam JH. Long-term effects of water-soluble dietary fiber in the management of hypercholesterolemia in healthy men and women. Am J Cardiol 1997;79:34-7. View abstract.
Jensen CD, Spiller GA, Gates JE, et al. The effect of acacia gum and a water-soluble dietary fiber mixture on blood lipids in humans. J Am Coll Nutr 1993;12:147-54. View abstract.
Juhász AE, Greff D, Teutsch B, et al. Galactomannans are the most effective soluble dietary fibers in type 2 diabetes: a systematic review and network meta-analysis. Am J Clin Nutr 2023;117(2):266-277. View abstract.
Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. View abstract.
Khossousi A, Binns CW, Dhaliwal SS, Pal S. The acute effects of psyllium on postprandial lipaemia and thermogenesis in overweight and obese men. Br J Nutr 2008;99:1068-75. View abstract.
Kumar A, Kumar N, Vij JC, et al. Optimum dosage of ispaghula husk in patients with irritable bowel syndrome: correlation of symptom relief with whole gut transit time and stool weight. Gut 1987;28:150-5. View abstract.
Kwiterovich PO. The role of fiber in the treatment of hypercholesterolemia in children and adolescents. Pediatrics 1995;96:1005-9. View abstract.
Lai H, Li Y, He Y, et al. Effects of dietary fibers or probiotics on functional constipation symptoms and roles of gut microbiota: a double-blinded randomized placebo trial. Gut Microbes 2023;15(1):2197837. View abstract.
Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. View abstract.
Leathwood PD, Chauffard F, Heck E, Munoz-Box R. Aqueous extract of valerian root (Valeriana officinalis L.) improves sleep quality in man. Pharmacol Biochem Behav 1982;17:65-71. View abstract.
Lerman Garber I, Lagunas M, Sienra Perez JC, et al. The effect of psyllium plantago in slightly to moderately hypercholesterolemic patients. Arch Inst Cardiol Mex 1990;60:535-9. View abstract.
Lertpipopmetha K, Kongkamol C, Sripongpun P. Effect of Psyllium Fiber Supplementation on Diarrhea Incidence in Enteral Tube-Fed Patients: A Prospective, Randomized, and Controlled Trial. JPEN J Parenter Enteral Nutr 2019;43(6):759-67. doi: 10.1002/jpen.1489. View abstract.
Levin EG, Miller VT, Muesing RA, et al. Comparison of psyllium hydrophilic mucilloid and cellulose as adjuncts to a prudent diet in the treatment of mild to moderate hypercholesterolemia. Arch Intern Med 1990;150:1822-7. View abstract.
Lipsky H, Gloger M, Frishman WH. Dietary fiber for reducing blood cholesterol. J Clin Pharmacol 1990;30(8):699-703. View abstract.
Little P, Trafford L. Dietary fibre and renal failure: comparison of sterculia and ispaghula. Clin Nephrol 1991;36:309. View abstract.
Longstreth GF, Fox DD, Youkeles L, et al. Psyllium therapy in the irritable bowel syndrome. A double-blind trial. Ann Intern Med 1981;95:53-6. View abstract.
López JC, Villanueva R, Martínez-Hernández D, Albaladejo R, Regidor E, Calle ME. Plantago ovata consumption and colorectal mortality in Spain, 1995-2000. J Epidemiol 2009;19(4):206-11. View abstract.
Maciejko JJ, Brazg R, Shah A, et al. Psyllium for the reduction of cholestyramine-associated gastrointestinal symptoms in the treatment of primary hypercholesterolemia. Arch Fam Med 1994;3:955-60.. View abstract.
MacMahon M, Carless J. Ispaghula husk in the treatment of hypercholesterolaemia: a double-blind controlled study. J Cardiovasc Risk. 1998 Jun;5:167-72. View abstract.
Maheshwari D, Hall CD, Jia X, et al. The Effect of Preoperative Fiber on Postoperative Bowel Function After Pelvic Reconstructive Surgery: A Randomized Controlled Trial. Urogynecology (Hagerstown) 2022;28(8):554-560. View abstract.
Marlett JA, Kajs TM, Fischer MH. An unfermented gel component of psyllium seed husk promotes laxation as a lubricant in humans. Am J Clin Nutr 2000;72:784-9. View abstract.
Marlett JA, Li BU, Patrow CJ, Bass P. Comparative laxation of psyllium with and without senna in an ambulatory constipated population. Am J Gastroenterol 1987;82:333-7. View abstract.
Marteau P, Flourie B, Cherbut C, et al. Digestibility and bulking effect of ispaghula husks in healthy humans. Gut 1994;35:1747-52.. View abstract.
McRorie JW, Daggy BP, Morel JG, et al. Psyllium is superior to docusate sodium for treatment of chronic constipation. Aliment Pharmacol Ther 1998;12:491-7.. View abstract.
Menees SB, Jackson K, Baker JR, et al. A Randomized Pilot Study to Compare the Effectiveness of a Low FODMAP Diet vs Psyllium in Patients With Fecal Incontinence and Loose Stools. Clin Transl Gastroenterol 2022;13(3):e00454. View abstract.
Menon J, Thapa BR, Kumari R, Kadyada SP, Rana S, Lal SB. EFFICACY OF ORAL PSYLLIUM IN PEDIATRIC IRRITABLE BOWEL SYNDROME : A DOUBLE BLIND RANDOMISED CONTROL TRIAL. J Pediatr Gastroenterol Nutr 2022. View abstract.
Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. View abstract.
Misra SP, Thorat VK, Sachdev GK, Anand BS. Long-term treatment of irritable bowel syndrome: results of a randomized controlled trial. Q J Med 1989:73:931-9. View abstract.
Moesgaard F, Nielsen ML, Hansen JB, et al. High-fiber diet reduces bleeding and pain in patients with hemorrhoids: a double-blind trial of Vi-Siblin. Dis Colon Rectum. 1982 Jul-Aug;25(5):454-6. View abstract.
Moreyra AE, Wilson AC, Koraym A. Effect of Combining Psyllium Fiber With Simvastatin in Lowering Cholesterol. Arch Intern Med 2005;165:1161-6. View abstract.
Morgan MS, Arlian LG, Vyszenski-Moher DL, et al. English plantain and psyllium: lack of cross-allergenicity by crossed immunoelectrophoresis. Ann Allergy Asthma Immunol 1995;75:351-9. View abstract.
Morozov S, Isakov V, Konovalova M. Fiber-enriched diet helps to control symptoms and improves esophageal motility in patients with non-erosive gastroesophageal reflux disease. World J Gastroenterol. 2018;24(21):2291-2299. View abstract.
Neal GW, Balm TK. Synergistic effects of psyllium in the dietary treatment of hypercholesterolemia. South Med J 1990;83:1131-7. View abstract.
Nigam P, Kapoor KK, Rastog CK, et al. Different therapeutic regimens in irritable bowel syndrome. J Assoc Physicians India. 1984 Dec;32(12):1041-4. View abstract.
Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9.. View abstract.
Noureddin S, Mohsen J, Payman A. Effects of psyllium vs. placebo on constipation, weight, glycemia, and lipids: A randomized trial in patients with type 2 diabetes and chronic constipation. Complement Ther Med. 2018;40:1-7. View abstract.
Odes HS, Madar Z. A double-blind trial of a celandin, aloevera and psyllium laxative preparation in adult patients with constipation. Digestion. 1991;49(2):65-71.View abstract.
Olson BH, Anderson SM, Becker MP, et al. Psyllium-enriched cereals lower blood total cholesterol and LDL cholesterol, but not HDL cholesterol, in hypercholesterolemic adults: results of a meta-analysis. J Nutr 1997;127:1973-80. View abstract.
Pal S, Khossousi A, Binns C, et al. The effect of a fibre supplement compared to a healthy diet on body composition, lipids, glucose, insulin and other metabolic syndrome risk factors in overweight and obese individuals. Br J Nutr 2011;105:90-100. View abstract.
Pal S, Khossousi A, Binns C, et al. The effects of 12-week psyllium fibre supplementation or healthy diet on blood pressure and arterial stiffness in overweight and obese individuals. Br J Nutr. 2012 Mar;107(5):725-34. View abstract.
Pastors JG, Blaisdell PW, Balm TK, et al. Psyllium fiber reduces rise in postprandial glucose and insulin concentrations in patients with non-insulin-dependent diabetes. Am J Clin Nutr 1991;53:1431-5. View abstract.
Perez-Miranda M, Gomez-Cedenilla A, León-Colombo T, et al. Effect of fiber supplements on internal bleeding hemorrhoids. Hepatogastroenterology. 1996 Nov-Dec;43(12):1504-7. View abstract.
Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416. View abstract.
Prior A, Whorwell PJ. Double blind study of ispaghula in irritable bowel syndrome. Gut 1987;28:1510-3. View abstract.
Quitadamo P, Coccorullo P, Giannetti E, et al. A randomized, prospective, comparison study of a mixture of acacia fiber, psyllium fiber, and fructose vs polyethylene glycol 3350 with electrolytes for the treatment of chronic functional constipation in childhood. J Pediatr. 2012 Oct;161(4):710-5.e1. View abstract.
Qvitzau S, Matzen P, Madsen P. Treatment of chronic diarrhoea: loperamide versus ispaghula husk and calcium. Scand J Gastroenterol 1988;23:1237-40. View abstract.
Ritchie JA, Truelove SC. Treatment of irritable bowel syndrome with lorazepam, hyoscine butylbromide, and ispaghula husk. Br Med J. 1979 Feb 10;1(6160):376-8. View abstract.
Rivers CR, Kantor MA. Psyllium husk intake and risk of type 2 diabetes: an evidence-based scientific and regulatory review of a qualified health claim conducted by the US Food and Drug Administration. Nutr Rev 2020 Jan 22:nuz103. doi: 10.1093/nutrit/nuz103. Online ahead of print. View abstract.
Roberts DC, Truswell AS, Bencke A, et al. The cholesterol-lowering effect of a breakfast cereal containing psyllium fibre. Med J Aust 1994;161:660-4. View abstract.
Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. View abstract.
Rodriguez-Moran M, Guerrero-Romero F, Lazcano-Burciaga G. Lipid- and glucose-lowering efficacy of Plantago Psyllium in type II diabetes. J Diabetes Complications 1998;12:273-8. View abstract.
Roe DA, Kalkwarf H, Stevens J. Effect of fiber supplements on the apparent absorption of pharmacological doses of riboflavin. J Am Diet Assoc 1988;88:211-3.. View abstract.
Romero AL, Romero JE, Galaviz S, Fernandez ML. Cookies enriched with psyllium or oat bran lower plasma LDL cholesterol in normal and hypercholesterolemic men from Northern Mexico. J Am Coll Nutr 1998;17:601-8. View abstract.
Rossander L. Effect of dietary fiber on iron absorption in man. Scand J Gastroenterol Suppl 1987;129:68-72.. View abstract.
Sartore G1, Reitano R, Barison A, et al. The effects of psyllium on lipoproteins in type II diabetic patients. View abstract.
Schaller DR. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1073.
Schectman G, Hiatt J, Hartz A. Evaluation of the effectiveness of lipid-lowering therapy (bile acid sepquestrants, niacin, psyllium and lovastatin) for treating hypercholesterolemia in veterans. Am J Cardiol 1993;71:759-65. View abstract.
Schneider RP. Perdiem causes esophageal impaction and bezoars. South Med J 1989;82:1449-50. View abstract.
Schwesinger WH, Kurtin WE, Page CP, et al. Soluble dietary fiber protects against cholesterol gallstone formation. Am J Surg 1999;177:307-10. View abstract.
Segawa K, Kataoka T, Fukuo Y. Cholesterol-lowering effects of psyllium seed associated with urea metabolism. Biol Pharm Bull 1998;21:184-7. View abstract.
Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at https://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
Shahinfar H, Jayedi A, Torabynasab K, et al. Comparative effects of nutraceuticals on body weight in adults with overweight or obesity: A systematic review and network meta-analysis of 111 randomized clinical trials. Pharmacol Res 2023;196:106944. View abstract.
Shin S, Kim JH, Mun YH, Chung HS. Acute esophageal obstruction after ingestion of psyllium seed husk powder: A case report. World J Clin Cases 2022;10(7):2336-2340. View abstract.
Shulman LM, Minagar A, Weiner WJ. Perdiem causing esophageal obstruction in Parkinson's disease. Neurology 1999;52:670-1. View abstract.
Sierra M, Garcia JJ, Fernandez N, et al. Therapeutic effects of psyllium in type 2 diabetic patients. Eur J Clin Nutr 2002;56:830-42. View abstract.
Solà R, Godàs G, Ribalta J, et al. Effects of soluble fiber (Plantago ovata husk) on plasma lipids, lipoproteins, and apolipoproteins in men with ischemic heart disease. Am J Clin Nutr 2007;85(4):1157-63. View abstract.
Spence JD, Huff MW, Heidenheim P, et al. Combination therapy with colestipol and psyllium mucilloid in patients with hyperlipidemia. Ann Intern Med 1995;123:493-9. View abstract.
Sprecher DL, Harris BV, Goldberg AC, et al. Efficacy of psyllium in reducing serum cholesterol levels in hypercholesterolemic patients on high- or low-fat diets. Ann Intern Med 1993;119:545-54. View abstract.
Stoy DB, LaRosa JC, Brewer BK, et al. Cholesterol-lowering effects of ready-to-eat cereal containing psyllium. J Am Diet Assoc 1993;93:910-2. View abstract.
Strommen GL, Dorworth TE, Walker PR, et al. Treatment of suspected postcholecystectomy diarrhea with psyllium hydrophilic mucilloid. Clin Pharm 1990;9:206-8. View abstract.
Suhonen R, Kantola I, Bjorksten F. Anaphylactic shock due to ingestion of psyllium laxative. Allergy 1983;38:363-5. View abstract.
Summerbell CD, Manley P, Barnes D, Leeds A. The effects of psyllium on blood lipids in hypercholesterolaemic subjects. Journal Of Human Nutrition & Dietetics. 1994:7:147-151.
Tomás-Ridocci M, Añón R, Mínguez M, et al. [The efficacy of Plantago ovata as a regulator of intestinal transit. A double-blind study compared to placebo]. Rev Esp Enferm Dig. 1992 Jul;82(1):17-22. View abstract.
Tominaga Y, Hirayama I, Nonaka M, Yano T, Ishii M. Intestinal obstruction caused by consuming diet food containing psyllium. Acute Med Surg 2023;10(1):e846. View abstract.
Turnbull WH, Thomas HG. The effect of Plantago ovate seed containing preparation on appetite variables, nutrient and energy intake. Int J Obese Relat Metab Disord 1995;19:338-42. View abstract.
Uribe M, Dibildox M, Malpica S, et al. Beneficial effect of vegetable protein diet supplemented with psyllium plantago in patients with hepatic encephalopathy and diabetes mellitus (abstract). Gastroenterology 1985;88:901-7. View abstract.
Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. View abstract.
Washington N, Harris M, Mussellwhite A, Spiller RC. Moderation of lactulose-induced diarrhea by psyllium: effects on motility and fermentation. Am J Clin Nutr 1998;67:317-21. View abstract.
Wei ZH, Wang H, Chen XY, et al. Time- and dose-dependent effect of psyllium on serum lipids in mild-to-moderate hypercholesterolemia: a meta-analysis of controlled clinical trials. Eur J Clin Nutr. 2009 Jul;63:821-7. View abstract.
Weingand KW, Le NA, Kuzmak BR, et al. Effects of psyllium on cholesterol and low-density lipoprotein metabolism in subjects with hypercholesterolemia. Endocrinology and Metabolism 1997;4:141-50.
Williams CL, Bollella M, Spark A, Puder D. Soluble fiber enhances the hypocholesterolemic effect of the step I diet in childhood. J Am Coll Nutr 1995;14:251-7. View abstract.
Wolever TM, Jenkins DJ, Mueller S, et al. Method of administration influences the serum cholesterol-lowering effect of psyllium. Am J Clin Nutr 1994;59:1055-9. View abstract.
Wolever TM, Jenkins DJ, Mueller S, et al. Psyllium reduces blood lipids in men and women with hyperlipidemia. Am J Med Sci 1994;307:269-73. View abstract.
Wolever TM, Robb PA. Effect of guar, pectin, psyllium, soy polysaccharide, and cellulose on breath hydrogen and methane in healthy subjects. Am J Gastroenterol 1992:87:305-10. View abstract.
Wolever TM, ter Wal P, Spadafora P, Robb P. Guar, but not psyllium, increases breath methane and serum acetate concentrations in human subjects. Am J Clin Nutr 1992;55:719-22. View abstract.
Wolever TM, Vuksan V, Eshuis H, et al. Effect of method of administration of psyllium on glycemic response and carbohydrate digestibility. J Am Coll Nutr 1991;10:364-71. View abstract.
Xiao Z, Chen H, Zhang Y, et al. The effect of psyllium consumption on weight, body mass index, lipid profile, and glucose metabolism in diabetic patients: A systematic review and dose-response meta-analysis of randomized controlled trials. Phytother Res 2020 Jan 9. doi: 10.1002/ptr.6609. Online ahead of print. View abstract.
Ziai SA, Larijani B, Akhoondzadeh S, et al. Psyllium decreased serum glucose and glycosylated hemoglobin significantly in diabetic outpatients. J Ethnopharmacol. 2005 Nov 14;102(2):202-7. View abstract.
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